A new material with theoretical osteoinductive properties: experimental evaluation.

R. Giardino, R. Mongiorgi, G. Bertocchi, M. Fini, G. Giavaresi, S. Capelli

Research output: Contribution to journalArticlepeer-review


An intensive research for bone substitutes has been in progress for several decades in order to find a new ideal material for bone replacement. In the present study the Authors report some data on a new developed material in comparison with synthetic hydroxyapatite. The new material was characterised by means of a crystallographic spectroscopic and chemical study. An in vitro test was also performed using murine fibroblasts. The results of this preliminary study showed that the sintered material has an and beta-tricalcium-phosphate (TCP) lattice depending on thermal treatment in accordance with literature data. Moreover, it showed a high level of biocompatibility. Though it is still in an investigation stage, perhaps this biomaterial is a highly reactive and unstable compound that could interact with CO2 and H2O.

Original languageEnglish
Pages (from-to)315-322
Number of pages8
JournalBollettino della Societa Italiana di Biologia Sperimentale
Issue number12
Publication statusPublished - Dec 1994

ASJC Scopus subject areas

  • Medicine(all)


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