A new region of conservation is defined between human and mouse X chromosomes

Mary Beth Dinulos, Maria T. Bassi, Elena I. Rugarli, Verne Chapman, Andrea Ballabio, Christine M. Disteche

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Comparative mapping of the X chromosome in eutherian mammals has revealed distinct regions of conservation as well as evolutionary rearrangements between human and mouse. Recently, we and others mapped the murine homologue of CLCN4 (Chloride channel 4) to band F4 of the X chromosome in Mus spretus but to chromosome 7 in laboratory strains. We now report the mapping of the murine homologues of APXL (Apical protein Xenopus laevis- like) and OA1 (Ocular albinism type I), two genes that are located on the human X chromosome at band p22.3 and in close proximity to CLCN4. Interestingly, Oa1 and Apx1 map to hands F2-F3 in both M. spretus and the laboratory strain C57BL/6J, defining a new rearrangement between human and mouse X chromosomes.

Original languageEnglish
Pages (from-to)244-247
Number of pages4
JournalGenomics
Volume35
Issue number1
DOIs
Publication statusPublished - Jul 1 1996

Fingerprint

Chromosomes, Human, X
Chloride Channels
X Chromosome
Xenopus Proteins
Chromosomes, Human, Pair 7
Mammals
Hand
Genes

ASJC Scopus subject areas

  • Genetics

Cite this

Dinulos, M. B., Bassi, M. T., Rugarli, E. I., Chapman, V., Ballabio, A., & Disteche, C. M. (1996). A new region of conservation is defined between human and mouse X chromosomes. Genomics, 35(1), 244-247. https://doi.org/10.1006/geno.1996.0347

A new region of conservation is defined between human and mouse X chromosomes. / Dinulos, Mary Beth; Bassi, Maria T.; Rugarli, Elena I.; Chapman, Verne; Ballabio, Andrea; Disteche, Christine M.

In: Genomics, Vol. 35, No. 1, 01.07.1996, p. 244-247.

Research output: Contribution to journalArticle

Dinulos, MB, Bassi, MT, Rugarli, EI, Chapman, V, Ballabio, A & Disteche, CM 1996, 'A new region of conservation is defined between human and mouse X chromosomes', Genomics, vol. 35, no. 1, pp. 244-247. https://doi.org/10.1006/geno.1996.0347
Dinulos MB, Bassi MT, Rugarli EI, Chapman V, Ballabio A, Disteche CM. A new region of conservation is defined between human and mouse X chromosomes. Genomics. 1996 Jul 1;35(1):244-247. https://doi.org/10.1006/geno.1996.0347
Dinulos, Mary Beth ; Bassi, Maria T. ; Rugarli, Elena I. ; Chapman, Verne ; Ballabio, Andrea ; Disteche, Christine M. / A new region of conservation is defined between human and mouse X chromosomes. In: Genomics. 1996 ; Vol. 35, No. 1. pp. 244-247.
@article{82b07518aaa54b4d8cb3d29502e6965f,
title = "A new region of conservation is defined between human and mouse X chromosomes",
abstract = "Comparative mapping of the X chromosome in eutherian mammals has revealed distinct regions of conservation as well as evolutionary rearrangements between human and mouse. Recently, we and others mapped the murine homologue of CLCN4 (Chloride channel 4) to band F4 of the X chromosome in Mus spretus but to chromosome 7 in laboratory strains. We now report the mapping of the murine homologues of APXL (Apical protein Xenopus laevis- like) and OA1 (Ocular albinism type I), two genes that are located on the human X chromosome at band p22.3 and in close proximity to CLCN4. Interestingly, Oa1 and Apx1 map to hands F2-F3 in both M. spretus and the laboratory strain C57BL/6J, defining a new rearrangement between human and mouse X chromosomes.",
author = "Dinulos, {Mary Beth} and Bassi, {Maria T.} and Rugarli, {Elena I.} and Verne Chapman and Andrea Ballabio and Disteche, {Christine M.}",
year = "1996",
month = "7",
day = "1",
doi = "10.1006/geno.1996.0347",
language = "English",
volume = "35",
pages = "244--247",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - A new region of conservation is defined between human and mouse X chromosomes

AU - Dinulos, Mary Beth

AU - Bassi, Maria T.

AU - Rugarli, Elena I.

AU - Chapman, Verne

AU - Ballabio, Andrea

AU - Disteche, Christine M.

PY - 1996/7/1

Y1 - 1996/7/1

N2 - Comparative mapping of the X chromosome in eutherian mammals has revealed distinct regions of conservation as well as evolutionary rearrangements between human and mouse. Recently, we and others mapped the murine homologue of CLCN4 (Chloride channel 4) to band F4 of the X chromosome in Mus spretus but to chromosome 7 in laboratory strains. We now report the mapping of the murine homologues of APXL (Apical protein Xenopus laevis- like) and OA1 (Ocular albinism type I), two genes that are located on the human X chromosome at band p22.3 and in close proximity to CLCN4. Interestingly, Oa1 and Apx1 map to hands F2-F3 in both M. spretus and the laboratory strain C57BL/6J, defining a new rearrangement between human and mouse X chromosomes.

AB - Comparative mapping of the X chromosome in eutherian mammals has revealed distinct regions of conservation as well as evolutionary rearrangements between human and mouse. Recently, we and others mapped the murine homologue of CLCN4 (Chloride channel 4) to band F4 of the X chromosome in Mus spretus but to chromosome 7 in laboratory strains. We now report the mapping of the murine homologues of APXL (Apical protein Xenopus laevis- like) and OA1 (Ocular albinism type I), two genes that are located on the human X chromosome at band p22.3 and in close proximity to CLCN4. Interestingly, Oa1 and Apx1 map to hands F2-F3 in both M. spretus and the laboratory strain C57BL/6J, defining a new rearrangement between human and mouse X chromosomes.

UR - http://www.scopus.com/inward/record.url?scp=0030200922&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030200922&partnerID=8YFLogxK

U2 - 10.1006/geno.1996.0347

DO - 10.1006/geno.1996.0347

M3 - Article

C2 - 8661129

AN - SCOPUS:0030200922

VL - 35

SP - 244

EP - 247

JO - Genomics

JF - Genomics

SN - 0888-7543

IS - 1

ER -