Nuove strategie di stadiazione endoscopica nel carcinoma laringeo: La multistep endoscopy

Translated title of the contribution: A new strategy for endoscopic staging of laryngeal carcinoma: Multistep endoscopy

E. Crosetti, F. Pilolli, G. Succo

Research output: Contribution to journalArticle

Abstract

At present, it is difficult to identify a gold standard for endoscopic staging of laryngeal cancer, especially considering the large number of endoscopic instruments available. We have coined the term multistep endoscopy to describe a method for staging laryngeal precancerous and neoplastic lesions that sequentially uses several endoscopic tools including high definition white light endoscopy (HDTV), stroboscopy and autofluorescence endoscopy. During the period from November 2007 to November 2009, 140 patients with a suspect laryngeal lesion underwent multistep endoscopy at the Department of Otorhinolaryngology at Martini Hospital in Turin. All patients were subjected to a series of endoscopic examinations in indirect laryngoscopy (white light endoscopy coupled to a HDTV camera, laryngostroboscopy, indirect autofluorescence) followed by white light endoscopy coupled to a HDTV camera and autofluorescence in direct microlaryngoscopy. The aim of the present prospective study was to evaluate the utility of multistep endoscopy in the diagnostic work-up of laryngeal lesions. Multistep endoscopy showed a higher sensitivity and "biological" predictive value in early cancer and precancerous lesions of the larynx (sensitivity, 97.9%; specificity, 90.5%) compared to individual endoscopic tools. It allows for better therapeutic planning of superficial lesions and more accurate orientation when performing mapping biopsies on diffuse lesions. In our opinion, more widespread use of indirect autofluorescence endoscopy during follow-up may be warranted to search for synchronous/metachronous second tumours of the upper aerodigestive tract.

Original languageItalian
Pages (from-to)175-181
Number of pages7
JournalActa Otorhinolaryngologica Italica
Volume32
Issue number3
Publication statusPublished - Jun 2012

Fingerprint

Endoscopy
Carcinoma
Light
Stroboscopy
Laryngoscopy
Laryngeal Neoplasms
Otolaryngology
Larynx
Neoplasms
Prospective Studies
Biopsy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Nuove strategie di stadiazione endoscopica nel carcinoma laringeo : La multistep endoscopy. / Crosetti, E.; Pilolli, F.; Succo, G.

In: Acta Otorhinolaryngologica Italica, Vol. 32, No. 3, 06.2012, p. 175-181.

Research output: Contribution to journalArticle

@article{c0996829dece468ebe80acaafb565f82,
title = "Nuove strategie di stadiazione endoscopica nel carcinoma laringeo: La multistep endoscopy",
abstract = "At present, it is difficult to identify a gold standard for endoscopic staging of laryngeal cancer, especially considering the large number of endoscopic instruments available. We have coined the term multistep endoscopy to describe a method for staging laryngeal precancerous and neoplastic lesions that sequentially uses several endoscopic tools including high definition white light endoscopy (HDTV), stroboscopy and autofluorescence endoscopy. During the period from November 2007 to November 2009, 140 patients with a suspect laryngeal lesion underwent multistep endoscopy at the Department of Otorhinolaryngology at Martini Hospital in Turin. All patients were subjected to a series of endoscopic examinations in indirect laryngoscopy (white light endoscopy coupled to a HDTV camera, laryngostroboscopy, indirect autofluorescence) followed by white light endoscopy coupled to a HDTV camera and autofluorescence in direct microlaryngoscopy. The aim of the present prospective study was to evaluate the utility of multistep endoscopy in the diagnostic work-up of laryngeal lesions. Multistep endoscopy showed a higher sensitivity and {"}biological{"} predictive value in early cancer and precancerous lesions of the larynx (sensitivity, 97.9{\%}; specificity, 90.5{\%}) compared to individual endoscopic tools. It allows for better therapeutic planning of superficial lesions and more accurate orientation when performing mapping biopsies on diffuse lesions. In our opinion, more widespread use of indirect autofluorescence endoscopy during follow-up may be warranted to search for synchronous/metachronous second tumours of the upper aerodigestive tract.",
keywords = "Laryngeal cancer staging, Laryngeal endoscopy, Multistep endoscopy",
author = "E. Crosetti and F. Pilolli and G. Succo",
year = "2012",
month = "6",
language = "Italian",
volume = "32",
pages = "175--181",
journal = "Acta Otorhinolaryngologica Italica",
issn = "0392-100X",
publisher = "Pacini Editore s.r.l.",
number = "3",

}

TY - JOUR

T1 - Nuove strategie di stadiazione endoscopica nel carcinoma laringeo

T2 - La multistep endoscopy

AU - Crosetti, E.

AU - Pilolli, F.

AU - Succo, G.

PY - 2012/6

Y1 - 2012/6

N2 - At present, it is difficult to identify a gold standard for endoscopic staging of laryngeal cancer, especially considering the large number of endoscopic instruments available. We have coined the term multistep endoscopy to describe a method for staging laryngeal precancerous and neoplastic lesions that sequentially uses several endoscopic tools including high definition white light endoscopy (HDTV), stroboscopy and autofluorescence endoscopy. During the period from November 2007 to November 2009, 140 patients with a suspect laryngeal lesion underwent multistep endoscopy at the Department of Otorhinolaryngology at Martini Hospital in Turin. All patients were subjected to a series of endoscopic examinations in indirect laryngoscopy (white light endoscopy coupled to a HDTV camera, laryngostroboscopy, indirect autofluorescence) followed by white light endoscopy coupled to a HDTV camera and autofluorescence in direct microlaryngoscopy. The aim of the present prospective study was to evaluate the utility of multistep endoscopy in the diagnostic work-up of laryngeal lesions. Multistep endoscopy showed a higher sensitivity and "biological" predictive value in early cancer and precancerous lesions of the larynx (sensitivity, 97.9%; specificity, 90.5%) compared to individual endoscopic tools. It allows for better therapeutic planning of superficial lesions and more accurate orientation when performing mapping biopsies on diffuse lesions. In our opinion, more widespread use of indirect autofluorescence endoscopy during follow-up may be warranted to search for synchronous/metachronous second tumours of the upper aerodigestive tract.

AB - At present, it is difficult to identify a gold standard for endoscopic staging of laryngeal cancer, especially considering the large number of endoscopic instruments available. We have coined the term multistep endoscopy to describe a method for staging laryngeal precancerous and neoplastic lesions that sequentially uses several endoscopic tools including high definition white light endoscopy (HDTV), stroboscopy and autofluorescence endoscopy. During the period from November 2007 to November 2009, 140 patients with a suspect laryngeal lesion underwent multistep endoscopy at the Department of Otorhinolaryngology at Martini Hospital in Turin. All patients were subjected to a series of endoscopic examinations in indirect laryngoscopy (white light endoscopy coupled to a HDTV camera, laryngostroboscopy, indirect autofluorescence) followed by white light endoscopy coupled to a HDTV camera and autofluorescence in direct microlaryngoscopy. The aim of the present prospective study was to evaluate the utility of multistep endoscopy in the diagnostic work-up of laryngeal lesions. Multistep endoscopy showed a higher sensitivity and "biological" predictive value in early cancer and precancerous lesions of the larynx (sensitivity, 97.9%; specificity, 90.5%) compared to individual endoscopic tools. It allows for better therapeutic planning of superficial lesions and more accurate orientation when performing mapping biopsies on diffuse lesions. In our opinion, more widespread use of indirect autofluorescence endoscopy during follow-up may be warranted to search for synchronous/metachronous second tumours of the upper aerodigestive tract.

KW - Laryngeal cancer staging

KW - Laryngeal endoscopy

KW - Multistep endoscopy

UR - http://www.scopus.com/inward/record.url?scp=84861745281&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861745281&partnerID=8YFLogxK

M3 - Articolo

C2 - 22767983

AN - SCOPUS:84861745281

VL - 32

SP - 175

EP - 181

JO - Acta Otorhinolaryngologica Italica

JF - Acta Otorhinolaryngologica Italica

SN - 0392-100X

IS - 3

ER -