A novel form of non-X-linked hyperigm associated with growth and pubertal disturbances and with lymphoma development

Viviana Moschese, Jiri Lintzman, Francesco Callea, Loredana Chini, Rita Devito, Rita Carsetti, Silvia Di Cesare, Frédéric Geissman, Nicole Brousse, Paolo Rossi, Anne Durandy

Research output: Contribution to journalArticlepeer-review

Abstract

HyperIgM syndrome is a heterogenous immunodeficiency characterized by impaired class-switch recombination due to different molecular abnormalities. We report on two female patients affected by a novel syndrome associating HIGM, growth and pubertal disturbances, and severe lymphoid hyperplasia with eventual development into lymphomas, suggesting a DNA repair defect.

Original languageEnglish
Pages (from-to)404-406
Number of pages3
JournalJournal of Pediatrics
Volume148
Issue number3
DOIs
Publication statusPublished - Mar 2006

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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