A nucleotide deletion in exon 4 is responsible for an HLA-A null allele (A*0105N)

Francesca Poli, P. Bianchi, M. Scalamogna, L. Crespiatico, N. Ghidoli, G. Puglisi, G. Sirchia

Research output: Contribution to journalArticlepeer-review

Abstract

We report herein the identification of a new HLA-A null allele. This allele, A*0105N, was detected during histocompatibility testing of a cord blood donor and the respective mother. Serologic typing results contrasted those obtained with DNA typing that alone showed the presence of HLA-A*01. This A*0105N was due to a nucleotide deletion in exon 4 that altered the reading frame, causing a premature termination.

Original languageEnglish
Pages (from-to)300-302
Number of pages3
JournalTissue Antigens
Volume54
Issue number3
DOIs
Publication statusPublished - 1999

Keywords

  • HLA-A null allele
  • MHC

ASJC Scopus subject areas

  • Immunology
  • Cell Biology

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