A nutrition-based approach to epidermolysis bullosa: Causes, assessments, requirements and management

Simona Salera, Gianluca Tadini, Donata Rossetti, Francesca Sofia Grassi, Paola Marchisio, Carlo Agostoni, Claudia Giavoli, Giulia Rodari, Sophie Guez

Research output: Contribution to journalReview article

Abstract

Inherited epidermolysis bullosa (EB) is a clinically and genetically heterogeneous group of rare diseases characterized by skin and mucous membrane fragility. EB primarily involves the skin and, in specific subtypes, the mucous membrane, resulting in complications which can strongly affect nutritional status (e.g. gastrointestinal complications, hand deformities, pain). The aims of nutritional support mainly include improving nutritional status, alleviating the stress of oral feeding and minimizing nutritional deficiencies, thus consequently improving growth, pubertal development, bowel function, immune status and wound healing. The aim of this review is to discuss knowledge of different aspects of the disease related to nutrition and growth.

Original languageEnglish
Pages (from-to)343-352
JournalClinical Nutrition
Volume39
Issue number2
DOIs
Publication statusPublished - 2020

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Keywords

  • Enteral nutrition
  • Epidermolysis bullosa
  • Growth retardation
  • Hypercatabolism
  • Nutritional status
  • Undernutrition

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Critical Care and Intensive Care Medicine

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