A Pictorial Ultrasound Essay of Gestational Trophoblastic Disease

Paolo Cavoretto, Raffaella Cioffi, Giorgia Mangili, Micaela Petrone, Alice Bergamini, Emanuela Rabaiotti, Luca Valsecchi, Massimo Candiani, Michael J. Seckl

Research output: Contribution to journalReview articlepeer-review


Gestational trophoblastic disease (GTD) includes a wide variety of clinical and histopathologic entities that require prompt identification and definition by the integration of clinical, laboratory, and imaging data. Recently, the role of grayscale ultrasound and spectral and power/color Doppler techniques has become pivotal in the diagnosis, staging, and management of GTD, thanks to both technical improvements and the growing expertise of dedicated operators. The aim of this essay is to summarize the most recent data on the ultrasound and Doppler findings of GTD and to provide a pictorial overview, including useful prognostic and therapeutic implications for clinical practice.

Original languageEnglish
Pages (from-to)597-613
Number of pages17
JournalJournal of Ultrasound in Medicine
Issue number3
Publication statusPublished - Mar 2020


  • choriocarcinoma
  • Doppler
  • gestational trophoblastic disease
  • hydatidiform mole
  • invasive mole
  • ultrasound

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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