A population based seroepidemiological survey of Chlamydia pneumoniae infections in schoolchildren

G. Dal Molin, B. Longo, T. Not, A. Poli, C. Campello

Research output: Contribution to journalArticle

Abstract

Aim: A serosurvey was carried out in schoolchildren from a northeastern area of Italy to define the burden of Chlamydia pneumoniae infection. Methods: A sample of 649 schoolchildren underwent a simplified version of the International Study of Asthma and Allergies in Childhood questionnaire and IgG and IgA antibodies were investigated using an enzyme immunoassay, followed by a microimmunofluorescence assay in reactive sera. Results: Of the children examined, 29% and 19.7% had IgG and IgA antibodies, respectively. The IgG prevalence increased with age. No other sociodemographical variable was related to C pneumoniae infection. An association was established between IgA prevalence and previous otitis media. Conclusions: A mesoendemic (intermediate between high and low endemic level) pattern of C pneumoniae infection is present in schoolchildren from this area and the prevalence rate is related to age. Moreover, this is the first epidemiological evidence of the role of C pneumoniae in otitis.

Original languageEnglish
Pages (from-to)617-620
Number of pages4
JournalJournal of Clinical Pathology
Volume58
Issue number6
DOIs
Publication statusPublished - Jun 2005

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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