A possible connective tissue primary lymphoepithelioma-like carcinoma (LELC)

G. Aurilio, V. Ricci, F. De Vita, M. Fasano, N. Fazio, M. Orditura, L. Funicelli, G. De Luca, D. Iasevoli, F. Iovino, F. Ciardiello, G. Conzo, F. Nolè, M. G. Lamendola

Research output: Contribution to journalArticle

Abstract

Lymphoepithelial carcinoma is an undifferentiated nasopharyngeal carcinoma with lymphoid stroma and non-keratinizing squamous cells with distinctive clinical, epidemiological and etiological features. Conversely, lymphoepithelioma-like carcinomas (LELCs) are carcinomas that arise outside the nasopharynx but resemble a lymphoepithelioma histologically. In this case study, LELC presentation in connective tissue (left sternocleidomastoid muscle) is peculiar and unusual, but its diagnosis is supported by histological findings and clinical history, especially long disease free survival and no primary lesions in nasopharynx and lung district. We also discuss the pathogenesis, hypothesizing an embryological theory. To our knowledge, it could be the first reported case of a primary connective tissue LELC to the neck.

Original languageEnglish
Article number197
Journalecancermedicalscience
Volume4
Issue number1
DOIs
Publication statusPublished - Dec 22 2010

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Connective Tissue
Carcinoma
Nasopharynx
Disease-Free Survival
Neck
Epithelial Cells
Muscles
Lung

Keywords

  • Lymphoepithelioma
  • Lymphoepithelioma-like carcinoma (lelc)
  • Neck mass

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

A possible connective tissue primary lymphoepithelioma-like carcinoma (LELC). / Aurilio, G.; Ricci, V.; De Vita, F.; Fasano, M.; Fazio, N.; Orditura, M.; Funicelli, L.; De Luca, G.; Iasevoli, D.; Iovino, F.; Ciardiello, F.; Conzo, G.; Nolè, F.; Lamendola, M. G.

In: ecancermedicalscience, Vol. 4, No. 1, 197, 22.12.2010.

Research output: Contribution to journalArticle

Aurilio, G, Ricci, V, De Vita, F, Fasano, M, Fazio, N, Orditura, M, Funicelli, L, De Luca, G, Iasevoli, D, Iovino, F, Ciardiello, F, Conzo, G, Nolè, F & Lamendola, MG 2010, 'A possible connective tissue primary lymphoepithelioma-like carcinoma (LELC)', ecancermedicalscience, vol. 4, no. 1, 197. https://doi.org/10.3332/ecancer.2010.197
Aurilio, G. ; Ricci, V. ; De Vita, F. ; Fasano, M. ; Fazio, N. ; Orditura, M. ; Funicelli, L. ; De Luca, G. ; Iasevoli, D. ; Iovino, F. ; Ciardiello, F. ; Conzo, G. ; Nolè, F. ; Lamendola, M. G. / A possible connective tissue primary lymphoepithelioma-like carcinoma (LELC). In: ecancermedicalscience. 2010 ; Vol. 4, No. 1.
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AU - Orditura, M.

AU - Funicelli, L.

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