A post-marketing study on immunomodulating treatments for relapsing-remitting multiple sclerosis in Lombardia: Preliminary results

C. Milanese, E. Beghi, L. Giordano, L. La Mantia, N. Mascoli, P. Confalonieri, D. Baldini, R. Bergamaschi, G. Bianchi, G. Cavaletti, R. Clerici, C. Cordioli, E. Ferrari, P. Gambaro, A. Ghezzi, L. Lo Russo, V. Martinelli, R. Palumbo, P. Perrone, P. PrevidiA. Protti, M. Rezzonico, M. Robotti, M. R. Rottoli, E. Scarpini

Research output: Contribution to journalArticle

Abstract

The preliminary results of a post-marketing study on relapsing-remitting multiple sclerosis patients treated with immunomodulating agents attending the Lombardia Region's Multiple Sclerosis Centers are presented. A total of 294 patients treated with Betaferon (67), Avonex (115), Rebif 22 (45), Rebif 44 (18) and Copaxone (49) were included. Relapse frequency consistently decreases at 1 year and continues to decrease after 5 years of treatment, without differences between therapeutic groups. Eighty-seven out of 294 patients (29.6%) discontinued treatment for different reasons. Forty-eight of them shifted to a second therapeutic agent. A different trend, to lower or higher doses of interferon or immunosuppression, according to reasons of discontinuation, was observed.

Original languageEnglish
JournalNeurological Sciences
Volume26
Issue numberSUPPL. 4
DOIs
Publication statusPublished - Dec 2005

Keywords

  • Copolymer 1
  • Interferons
  • Relapsing-remitting multiple sclerosis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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    Milanese, C., Beghi, E., Giordano, L., La Mantia, L., Mascoli, N., Confalonieri, P., Baldini, D., Bergamaschi, R., Bianchi, G., Cavaletti, G., Clerici, R., Cordioli, C., Ferrari, E., Gambaro, P., Ghezzi, A., Lo Russo, L., Martinelli, V., Palumbo, R., Perrone, P., ... Scarpini, E. (2005). A post-marketing study on immunomodulating treatments for relapsing-remitting multiple sclerosis in Lombardia: Preliminary results. Neurological Sciences, 26(SUPPL. 4). https://doi.org/10.1007/s10072-005-0509-3