TY - JOUR
T1 - A practical management of children with antibiotic allergy
AU - Calamelli, Elisabetta
AU - Caffarelli, Carlo
AU - Franceschini, Fabrizio
AU - Saretta, Francesca
AU - Cardinale, Fabio
AU - Bernardini, Roberto
AU - Liotti, Lucia
AU - Mori, Francesca
AU - Crisafulli, Giuseppe
AU - Caimmi, Silvia
AU - Bottau, Paolo
PY - 2019/1/1
Y1 - 2019/1/1
N2 - About 10% of the parents reported that their children are allergic to one drug and the betalactam antibiotics are the most frequently suspected. Even if most of the adverse events following antibiotic prescriptions to children are considered allergic, after a full allergy work-up only a few of the suspected reactions are confirmed. For this reason, many children are incorrectly labelled as “allergic” and this represents an important challenge for the choice of the antibiotic therapy in these “labelled” children, who are frequently improperly deprived of narrow-spectrum antibiotics because considered as allergic. When an allergic reaction is suspected a precise diagnosis and a choice of a safe and effective alternative is essential for the future antibiotic option. In the light of this, the main aim of this paper is to try to provide a practical approach to managing the individuals who have reported adverse reactions to antibiotics. (www.actabiomedica.it).
AB - About 10% of the parents reported that their children are allergic to one drug and the betalactam antibiotics are the most frequently suspected. Even if most of the adverse events following antibiotic prescriptions to children are considered allergic, after a full allergy work-up only a few of the suspected reactions are confirmed. For this reason, many children are incorrectly labelled as “allergic” and this represents an important challenge for the choice of the antibiotic therapy in these “labelled” children, who are frequently improperly deprived of narrow-spectrum antibiotics because considered as allergic. When an allergic reaction is suspected a precise diagnosis and a choice of a safe and effective alternative is essential for the future antibiotic option. In the light of this, the main aim of this paper is to try to provide a practical approach to managing the individuals who have reported adverse reactions to antibiotics. (www.actabiomedica.it).
KW - Antibiotic allergy
KW - Basophil activation test
KW - Betalactam
KW - Children
KW - Drug adverse reaction
KW - Drug provocation test
KW - Hypersensitivity reactions
KW - Skin test
KW - Specific IgE
UR - http://www.scopus.com/inward/record.url?scp=85062415162&partnerID=8YFLogxK
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U2 - 10.23750/abm.v90i3-S.8157
DO - 10.23750/abm.v90i3-S.8157
M3 - Review article
C2 - 30830057
AN - SCOPUS:85062415162
VL - 90
SP - 11
EP - 19
JO - Acta Biomedica de l'Ateneo Parmense
JF - Acta Biomedica de l'Ateneo Parmense
SN - 0392-4203
ER -