A preliminary note on inhibiting effect of α-tocopherol (Vit. E) on protein glycation

A. Ceriello, D. Giugliano, A. Quatraro, P. Dello Russo, R. Torella

Research output: Contribution to journalArticlepeer-review

Abstract

Human plasma albumin was incubated in 25 mM/l glucose at 37°C for up to seven days. Aliquots of this mixture were also incubated with α-tocopherol (Vitamin E) at 2 mg/dl, 4 mg/dl and 8 mg/dl, respectively. Vitamin E inhibited protein glycation and, furthermore, shows a dose-dependent effect. This report suggests the possibility of using Vitamin E, at therapeutic doses, to obtain the inhibition of non-enzymatic glycation.

Original languageEnglish
Pages (from-to)40-42
Number of pages3
JournalDiabete et Metabolisme
Volume14
Issue number1
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

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