Hypertrophic Idiopathic Pachymeningitis (HIP) is a diagnosis of exclusion; patients with this disease display a chronic course, often with disabling headache and other neurological signs/symptoms. Therapy includes symptomatic treatment together with empirical administration of steroids and/or immunosuppressants. We report the case of a man with progressive IHP in whom chronic steroid treatment deferred detection of cerebrospinal fluid abnormalities highly suggestive of tubercular infection; after a brief wash-out from steroids, CSF hypoglycorrachia and increase in total protein - together with positive Tine-test - led, despite non-diagnostic meningeal biopsy - to antitubercular therapy with marked clinico-radiological improvement.
|Translated title of the contribution||A probable case of hypertrophic idiopathic pachimeningitis traited successfully with antitubercular therapy|
|Number of pages||5|
|Journal||Rivista Italiana di Neurobiologia|
|Publication status||Published - 2005|
ASJC Scopus subject areas
- Clinical Neurology