A proposal of a new nomogram for predicting upstaging in contemporary D’Amico low-risk prostate cancer patients

SR Leyh-Bannurah, Paolo Dell’Oglio, Z Tian, J Schiffmann, SF Shariat, N Suardi, F Montorsi, A Briganti, H Heinzer, H Huland, M Graefen, L Budäus, PI Karakiewicz

Research output: Contribution to journalArticle

Abstract

Purpose: Unfavorable prostate cancer (PCa) disease at final pathology affects at least 10 % of D’Amico low-risk patients. Thus, conservative therapies including active surveillance may be wrongfully applied. The purposes were to assess the rate of upstaging in a contemporary cohort of D’Amico low-risk PCa patients and to develop and externally validate a nomogram as upstaging prediction tool in two European cohorts. Methods: Analyses were restricted to 2007 patients who harbored low-risk PCa at ≥10-cores initial biopsy according to D’Amico classification (PSA
Original languageEnglish
Pages (from-to)189-197
Number of pages9
JournalWorld Journal of Urology
Volume35
Issue number2
DOIs
Publication statusPublished - 2017

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    Leyh-Bannurah, SR., Dell’Oglio, P., Tian, Z., Schiffmann, J., Shariat, SF., Suardi, N., Montorsi, F., Briganti, A., Heinzer, H., Huland, H., Graefen, M., Budäus, L., & Karakiewicz, PI. (2017). A proposal of a new nomogram for predicting upstaging in contemporary D’Amico low-risk prostate cancer patients. World Journal of Urology, 35(2), 189-197. https://doi.org/10.1007/s00345-016-1863-x