A prospective international Aspergillus terreus survey: An EFISG, ISHAM and ECMM joint study

B. Risslegger, T. Zoran, M. Lackner, M. Aigner, F. Sánchez-Reus, A. Rezusta, A. Chowdhary, S. J. Taj-Aldeen, M. C. Arendrup, S. Oliveri, D. P. Kontoyiannis, A. Alastruey-Izquierdo, K. Lagrou, G. Lo Cascio, J. F. Meis, W. Buzina, C. Farina, M. Drogari-Apiranthitou, A. Grancini, A. M. TortoranoB. Willinger, A. Hamprecht, E. Johnson, L. Klingspor, V. Arsic-Arsenijevic, O. A. Cornely, J. Meletiadis, W. Prammer, V. Tullio, J. J. Vehreschild, L. Trovato, R. E. Lewis, E. Segal, P. M. Rath, P. Hamal, M. Rodriguez-Iglesias, E. Roilides, S. Arikan-Akdagli, A. Chakrabarti, A. L. Colombo, M. S. Fernández, M. T. Martin-Gomez, H. Badali, G. Petrikkos, N. Klimko, S. M. Heimann, J. Houbraken, O. Uzun, M. Edlinger, S. de la Fuente, C. Lass-Flörl

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections. Methods: A total of 370 cases from 21 countries were evaluated. Results: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L). Conclusions: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.

Original languageEnglish
Pages (from-to)776.e1-776.e5
JournalClinical Microbiology and Infection
Volume23
Issue number10
DOIs
Publication statusPublished - 2017

Keywords

  • Aspergillus terreus
  • In vitrosusceptibility
  • Amphotericin B
  • Aspergillosis
  • Crytic species

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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