Abstract
Objectives: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections. Methods: A total of 370 cases from 21 countries were evaluated. Results: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L). Conclusions: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.
| Original language | English |
|---|---|
| Pages (from-to) | 776.e1-776.e5 |
| Journal | Clinical Microbiology and Infection |
| Volume | 23 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2017 |
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Keywords
- Aspergillus terreus
- In vitrosusceptibility
- Amphotericin B
- Aspergillosis
- Crytic species
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases
Cite this
A prospective international Aspergillus terreus survey : An EFISG, ISHAM and ECMM joint study. / Risslegger, B.; Zoran, T.; Lackner, M.; Aigner, M.; Sánchez-Reus, F.; Rezusta, A.; Chowdhary, A.; Taj-Aldeen, S. J.; Arendrup, M. C.; Oliveri, S.; Kontoyiannis, D. P.; Alastruey-Izquierdo, A.; Lagrou, K.; Lo Cascio, G.; Meis, J. F.; Buzina, W.; Farina, C.; Drogari-Apiranthitou, M.; Grancini, A.; Tortorano, A. M.; Willinger, B.; Hamprecht, A.; Johnson, E.; Klingspor, L.; Arsic-Arsenijevic, V.; Cornely, O. A.; Meletiadis, J.; Prammer, W.; Tullio, V.; Vehreschild, J. J.; Trovato, L.; Lewis, R. E.; Segal, E.; Rath, P. M.; Hamal, P.; Rodriguez-Iglesias, M.; Roilides, E.; Arikan-Akdagli, S.; Chakrabarti, A.; Colombo, A. L.; Fernández, M. S.; Martin-Gomez, M. T.; Badali, H.; Petrikkos, G.; Klimko, N.; Heimann, S. M.; Houbraken, J.; Uzun, O.; Edlinger, M.; Fuente, S. de la; Lass-Flörl, C.
In: Clinical Microbiology and Infection, Vol. 23, No. 10, 2017, p. 776.e1-776.e5.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A prospective international Aspergillus terreus survey
T2 - An EFISG, ISHAM and ECMM joint study
AU - Risslegger, B.
AU - Zoran, T.
AU - Lackner, M.
AU - Aigner, M.
AU - Sánchez-Reus, F.
AU - Rezusta, A.
AU - Chowdhary, A.
AU - Taj-Aldeen, S. J.
AU - Arendrup, M. C.
AU - Oliveri, S.
AU - Kontoyiannis, D. P.
AU - Alastruey-Izquierdo, A.
AU - Lagrou, K.
AU - Lo Cascio, G.
AU - Meis, J. F.
AU - Buzina, W.
AU - Farina, C.
AU - Drogari-Apiranthitou, M.
AU - Grancini, A.
AU - Tortorano, A. M.
AU - Willinger, B.
AU - Hamprecht, A.
AU - Johnson, E.
AU - Klingspor, L.
AU - Arsic-Arsenijevic, V.
AU - Cornely, O. A.
AU - Meletiadis, J.
AU - Prammer, W.
AU - Tullio, V.
AU - Vehreschild, J. J.
AU - Trovato, L.
AU - Lewis, R. E.
AU - Segal, E.
AU - Rath, P. M.
AU - Hamal, P.
AU - Rodriguez-Iglesias, M.
AU - Roilides, E.
AU - Arikan-Akdagli, S.
AU - Chakrabarti, A.
AU - Colombo, A. L.
AU - Fernández, M. S.
AU - Martin-Gomez, M. T.
AU - Badali, H.
AU - Petrikkos, G.
AU - Klimko, N.
AU - Heimann, S. M.
AU - Houbraken, J.
AU - Uzun, O.
AU - Edlinger, M.
AU - Fuente, S. de la
AU - Lass-Flörl, C.
PY - 2017
Y1 - 2017
N2 - Objectives: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections. Methods: A total of 370 cases from 21 countries were evaluated. Results: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L). Conclusions: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.
AB - Objectives: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections. Methods: A total of 370 cases from 21 countries were evaluated. Results: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L). Conclusions: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.
KW - Aspergillus terreus
KW - In vitrosusceptibility
KW - Amphotericin B
KW - Aspergillosis
KW - Crytic species
UR - http://www.scopus.com/inward/record.url?scp=85021237872&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021237872&partnerID=8YFLogxK
U2 - 10.1016/j.cmi.2017.04.012
DO - 10.1016/j.cmi.2017.04.012
M3 - Article
AN - SCOPUS:85021237872
VL - 23
SP - 776.e1-776.e5
JO - Clinical Microbiology and Infection
JF - Clinical Microbiology and Infection
SN - 1198-743X
IS - 10
ER -