Abstract
Objective: This study was undertaken to compare the quality of life (QoL) in women with early stage endometrial cancer treated with 2 different surgical approaches. Study design: Eighty-four women with clinical stage I endometrial cancer were enrolled in a prospective randomized controlled trial design and treated with laparoscopic or laparotomic approach. Another 40 women matched for demographic characteristics were studied as controls. In patients, before and after surgery, and in their matched controls, QoL was evaluated by using the Short-Form Healthy Survey (SF-36) and the climacteric symptoms using the Kupperman Index (KI). Results: After randomization, no difference was detected in data recorded between the groups. At entry, QoL was similar in both treatment groups but significantly (P <.05) worse in comparison with controls. Throughout the study, QoL was significantly (P <.05) higher in laparoscopic group versus laparotomic group. After KI adjustment our data did not change. Conclusion: In early stage endometrial cancer, the laparoscopic approach provides significant benefits compared with laparotomy in terms of QoL.
| Original language | English |
|---|---|
| Pages (from-to) | 1344-1352 |
| Number of pages | 9 |
| Journal | American Journal of Obstetrics and Gynecology |
| Volume | 193 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 2005 |
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Keywords
- Endometrial cancer
- Laparoscopy
- Laparotomy
- Quality of life
- Surgery
ASJC Scopus subject areas
- Medicine(all)
- Obstetrics and Gynaecology
Cite this
A prospective randomized comparison between laparoscopic and laparotomic approaches in women with early stage endometrial cancer : A focus on the quality of life. / Zullo, Fulvio; Palomba, Stefano; Russo, Tiziana; Falbo, Angela; Costantino, Marilena; Tolino, Achille; Zupi, Errico; Tagliaferri, Piersandro; Venuta, Salvatore.
In: American Journal of Obstetrics and Gynecology, Vol. 193, No. 4, 10.2005, p. 1344-1352.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A prospective randomized comparison between laparoscopic and laparotomic approaches in women with early stage endometrial cancer
T2 - A focus on the quality of life
AU - Zullo, Fulvio
AU - Palomba, Stefano
AU - Russo, Tiziana
AU - Falbo, Angela
AU - Costantino, Marilena
AU - Tolino, Achille
AU - Zupi, Errico
AU - Tagliaferri, Piersandro
AU - Venuta, Salvatore
PY - 2005/10
Y1 - 2005/10
N2 - Objective: This study was undertaken to compare the quality of life (QoL) in women with early stage endometrial cancer treated with 2 different surgical approaches. Study design: Eighty-four women with clinical stage I endometrial cancer were enrolled in a prospective randomized controlled trial design and treated with laparoscopic or laparotomic approach. Another 40 women matched for demographic characteristics were studied as controls. In patients, before and after surgery, and in their matched controls, QoL was evaluated by using the Short-Form Healthy Survey (SF-36) and the climacteric symptoms using the Kupperman Index (KI). Results: After randomization, no difference was detected in data recorded between the groups. At entry, QoL was similar in both treatment groups but significantly (P <.05) worse in comparison with controls. Throughout the study, QoL was significantly (P <.05) higher in laparoscopic group versus laparotomic group. After KI adjustment our data did not change. Conclusion: In early stage endometrial cancer, the laparoscopic approach provides significant benefits compared with laparotomy in terms of QoL.
AB - Objective: This study was undertaken to compare the quality of life (QoL) in women with early stage endometrial cancer treated with 2 different surgical approaches. Study design: Eighty-four women with clinical stage I endometrial cancer were enrolled in a prospective randomized controlled trial design and treated with laparoscopic or laparotomic approach. Another 40 women matched for demographic characteristics were studied as controls. In patients, before and after surgery, and in their matched controls, QoL was evaluated by using the Short-Form Healthy Survey (SF-36) and the climacteric symptoms using the Kupperman Index (KI). Results: After randomization, no difference was detected in data recorded between the groups. At entry, QoL was similar in both treatment groups but significantly (P <.05) worse in comparison with controls. Throughout the study, QoL was significantly (P <.05) higher in laparoscopic group versus laparotomic group. After KI adjustment our data did not change. Conclusion: In early stage endometrial cancer, the laparoscopic approach provides significant benefits compared with laparotomy in terms of QoL.
KW - Endometrial cancer
KW - Laparoscopy
KW - Laparotomy
KW - Quality of life
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=25844529454&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=25844529454&partnerID=8YFLogxK
U2 - 10.1016/j.ajog.2005.02.131
DO - 10.1016/j.ajog.2005.02.131
M3 - Article
C2 - 16202724
AN - SCOPUS:25844529454
VL - 193
SP - 1344
EP - 1352
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 4
ER -