A prospective study of the relationship between disease activity and psychologic distress in patients with inflammatory bowel disease

P. Porcelli, C. Leoci, V. Guerra

Research output: Contribution to journalArticle

109 Citations (Scopus)

Abstract

Background: The evaluation of psychologic states is very useful in the management of inflammatory bowel disease (IBD) patients, particularly when related to disease activity (DA). Our aim was to prospectively evaluate the relationship between psychologic distress and DA. Methods: DA and psychologic distress were evaluated in 104 IBD outpatients by means of clinical criteria and the Hospital Anxiety and Depression Scale (HADS) at base line and after 6 months. Patients were grouped in unchanged, improved, and worsened DA from base line to follow-up. Results: Repeated-measures ANOVA showed a significant group-by-time interaction for HADS anxiety (F = 89.6, P = 0.0001) and - depression (F = 3.67, P = 0.03) subscales. Conclusions: Over time changes in DA significantly affect psychologic distress and are closely related to corresponding increases and decreases in anxiety and depression in IBD patients. Our findings therefore suggest that the assessment of psychologic distress, particularly anxiety, should be included in the clinical management of IBD patients.

Original languageEnglish
Pages (from-to)792-796
Number of pages5
JournalScandinavian Journal of Gastroenterology
Volume31
Issue number8
Publication statusPublished - 1996

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Inflammatory Bowel Diseases
Anxiety
Prospective Studies
Depression
Analysis of Variance
Outpatients

Keywords

  • Disease activity
  • Health status
  • Inflammatory bowel disease
  • Psychologic stress

ASJC Scopus subject areas

  • Gastroenterology

Cite this

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abstract = "Background: The evaluation of psychologic states is very useful in the management of inflammatory bowel disease (IBD) patients, particularly when related to disease activity (DA). Our aim was to prospectively evaluate the relationship between psychologic distress and DA. Methods: DA and psychologic distress were evaluated in 104 IBD outpatients by means of clinical criteria and the Hospital Anxiety and Depression Scale (HADS) at base line and after 6 months. Patients were grouped in unchanged, improved, and worsened DA from base line to follow-up. Results: Repeated-measures ANOVA showed a significant group-by-time interaction for HADS anxiety (F = 89.6, P = 0.0001) and - depression (F = 3.67, P = 0.03) subscales. Conclusions: Over time changes in DA significantly affect psychologic distress and are closely related to corresponding increases and decreases in anxiety and depression in IBD patients. Our findings therefore suggest that the assessment of psychologic distress, particularly anxiety, should be included in the clinical management of IBD patients.",
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AU - Porcelli, P.

AU - Leoci, C.

AU - Guerra, V.

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N2 - Background: The evaluation of psychologic states is very useful in the management of inflammatory bowel disease (IBD) patients, particularly when related to disease activity (DA). Our aim was to prospectively evaluate the relationship between psychologic distress and DA. Methods: DA and psychologic distress were evaluated in 104 IBD outpatients by means of clinical criteria and the Hospital Anxiety and Depression Scale (HADS) at base line and after 6 months. Patients were grouped in unchanged, improved, and worsened DA from base line to follow-up. Results: Repeated-measures ANOVA showed a significant group-by-time interaction for HADS anxiety (F = 89.6, P = 0.0001) and - depression (F = 3.67, P = 0.03) subscales. Conclusions: Over time changes in DA significantly affect psychologic distress and are closely related to corresponding increases and decreases in anxiety and depression in IBD patients. Our findings therefore suggest that the assessment of psychologic distress, particularly anxiety, should be included in the clinical management of IBD patients.

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