A prospective study on 132 cases of ocular Palsy

A. Castelluccia, V. Nociti, G. Frisullo, A. P. Batocchi

Research output: Contribution to journalArticle


Objectives: In this prospective study, we used one diagnostic protocol to establish an early diagnosis in patients with ocular palsies in absence of other neurological findings. Materials and Methods: The study was performed on a consecutive series of 132 patients who visited our Neurological Department for ptosis and/or diplopia in absence of other neurological signs, using the same diagnostic protocol. Results: An etiological diagnosis was made in 74% of cases during a mean time of 17 ± 23 months from symptom onset. Myasthenia gravis was the most common diagnosis (n = 60, 45.5%). Thirty-four cases (26%) remained undiagnosed in spite of a follow-up lasting 32 ± 33 months on average. Conclusions: Identifying the cause of an isolated ocular palsy can be difficult, and an extended follow-up time does not aid in further establishment of the diagnosis.

Original languageEnglish
Pages (from-to)10-15
Number of pages6
JournalEuropean Neurology
Issue number1-2
Publication statusPublished - Aug 2013


  • Diplopia
  • Internuclear ophthalmoplegia
  • Ocular myasthenia
  • Ocular palsies
  • Ptosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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    Castelluccia, A., Nociti, V., Frisullo, G., & Batocchi, A. P. (2013). A prospective study on 132 cases of ocular Palsy. European Neurology, 70(1-2), 10-15. https://doi.org/10.1159/000348717