A randomized double-blind crossover trial of intravenous lidocaine in the treatment of neuropathic cancer pain

E. Bruera; C. Ripamonti; C. Brenneis; K. Macmillan; J. Hanson

A randomized double-blind crossover trial of intravenous lidocaine in the treatment of neuropathic cancer pain

E. Bruera, C. Ripamonti, C. Brenneis, K. Macmillan, J. Hanson

Fondazione IRCCS Istituto Nazionale dei Tumori

Research output: Contribution to journal › Article › peer-review

Abstract

In a randomized, double-blind, crossover study, we evaluated the effect of intravenous lidocaine (5 mg/kg body weight over 30 min) on the neuropathic pain of advanced cancer patients. Pain intensity, assessed by a visual analogue scale, did not show any significant difference between lidocaine and placebo infusion. The blinded choice of patients and investigators also suggested no significant improvement from lidocaine when given by this regimen. Intravenous lidocaine does not appear to have a significant analgesic effect on neuropathic cancer pain.

Original language	English
Pages (from-to)	138-140
Number of pages	3
Journal	Journal of Pain and Symptom Management
Volume	7
Issue number	3
Publication status	Published - 1992

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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abstract = "In a randomized, double-blind, crossover study, we evaluated the effect of intravenous lidocaine (5 mg/kg body weight over 30 min) on the neuropathic pain of advanced cancer patients. Pain intensity, assessed by a visual analogue scale, did not show any significant difference between lidocaine and placebo infusion. The blinded choice of patients and investigators also suggested no significant improvement from lidocaine when given by this regimen. Intravenous lidocaine does not appear to have a significant analgesic effect on neuropathic cancer pain.",

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AU - Brenneis, C.

AU - Macmillan, K.

AU - Hanson, J.

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A randomized double-blind crossover trial of intravenous lidocaine in the treatment of neuropathic cancer pain

Abstract

ASJC Scopus subject areas

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