A rare case of intravascular epithelioid hemangioendothelioma of the cephalic vein treated with surgery and postoperative radiation therapy: A case report and review of the literature

Maria Paola Ciliberti, Raffaella Caponio, Antonio Pascali, Gabriele Matichecchia, Marco Lioce

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2 Citations (Scopus)

Abstract

Introduction: Epithelioid hemangioendothelioma (EHE) is a rare endothelial tumor with an intermediate grade of malignancy. Few cases of primary vascular hemangioendothelioma have been described in the literature. Surgery is the treatment of choice, but radiation therapy and chemotherapy should also be considered in particular cases. Case presentation: We present the case of a 44-year-old Caucasian woman affected by EHE of the cephalic vein, treated by complete surgical removal of the mass and postoperative local radiation therapy. At 5-year follow-up, our patient is alive, with no signs of local or distant relapse and with no late radiation-related effects. Conclusions: Postoperative radiotherapy may play a role in cases in which tumor margins are close or cannot be assessed or when high-risk features are present.

Original languageEnglish
Article number91
JournalJournal of Medical Case Reports
Volume9
Issue number1
DOIs
Publication statusPublished - Apr 29 2015

Fingerprint

Epithelioid Hemangioendothelioma
Veins
Radiotherapy
Head
Hemangioendothelioma
Neoplasms
Radiation Effects
Blood Vessels
Recurrence
Drug Therapy
Therapeutics

Keywords

  • Cephalic vein
  • Epithelioid hemangioendothelioma
  • Intravascular
  • Radiotherapy
  • Review
  • Vascular

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "Introduction: Epithelioid hemangioendothelioma (EHE) is a rare endothelial tumor with an intermediate grade of malignancy. Few cases of primary vascular hemangioendothelioma have been described in the literature. Surgery is the treatment of choice, but radiation therapy and chemotherapy should also be considered in particular cases. Case presentation: We present the case of a 44-year-old Caucasian woman affected by EHE of the cephalic vein, treated by complete surgical removal of the mass and postoperative local radiation therapy. At 5-year follow-up, our patient is alive, with no signs of local or distant relapse and with no late radiation-related effects. Conclusions: Postoperative radiotherapy may play a role in cases in which tumor margins are close or cannot be assessed or when high-risk features are present.",
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AU - Ciliberti, Maria Paola

AU - Caponio, Raffaella

AU - Pascali, Antonio

AU - Matichecchia, Gabriele

AU - Lioce, Marco

PY - 2015/4/29

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N2 - Introduction: Epithelioid hemangioendothelioma (EHE) is a rare endothelial tumor with an intermediate grade of malignancy. Few cases of primary vascular hemangioendothelioma have been described in the literature. Surgery is the treatment of choice, but radiation therapy and chemotherapy should also be considered in particular cases. Case presentation: We present the case of a 44-year-old Caucasian woman affected by EHE of the cephalic vein, treated by complete surgical removal of the mass and postoperative local radiation therapy. At 5-year follow-up, our patient is alive, with no signs of local or distant relapse and with no late radiation-related effects. Conclusions: Postoperative radiotherapy may play a role in cases in which tumor margins are close or cannot be assessed or when high-risk features are present.

AB - Introduction: Epithelioid hemangioendothelioma (EHE) is a rare endothelial tumor with an intermediate grade of malignancy. Few cases of primary vascular hemangioendothelioma have been described in the literature. Surgery is the treatment of choice, but radiation therapy and chemotherapy should also be considered in particular cases. Case presentation: We present the case of a 44-year-old Caucasian woman affected by EHE of the cephalic vein, treated by complete surgical removal of the mass and postoperative local radiation therapy. At 5-year follow-up, our patient is alive, with no signs of local or distant relapse and with no late radiation-related effects. Conclusions: Postoperative radiotherapy may play a role in cases in which tumor margins are close or cannot be assessed or when high-risk features are present.

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KW - Radiotherapy

KW - Review

KW - Vascular

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