A rationale multidisciplinary approach for treatment of esophageal and gastroesophageal junction cancer: Accurate review of management and perspectives

Antonio Chiappa, Bruno Andreoni, Renzo Dionigi, Lorenzo Spaggiari, Diego Foschi, Gianluca Polvani, Roberto Orecchia, Nicola Fazio, Gabriella Pravettoni, Maria Laura Cossu, Domenico Galetta, Marco Venturino, Carlo Ferrari, Lorenzo Macone, Cristiano Crosta, Bernardo Bonanni, Roberto Biffi

Research output: Contribution to journalReview article

Abstract

Cancer of the esophagus and of gastroesophageal junction can be cured, even if with lacking cure rate. Different approaches have been developed, mostly when carcinoma has loco-regional pattern. Multimodality therapy showed a survival rate superior than 10% if compared to a single approach. This is a systematic review, carried to assess the following matters: Which therapeutic opportunities are available? Who could benefit of them? Which adverse reactions could possibly verify? How can physicians definitely choose the proper strategy? Which is the role of surgery? We mean to give either General Practitioner or specialists clear and efficient updates about current treatment of this tumour, starting from physical examination. Four eminent guidelines were consulted for our study: Cancer Care Ontario's Program in Evidence-Based Care, NCCN, Belgian Health Care Knowledge Centre and Esmo.

Original languageEnglish
Pages (from-to)161-168
Number of pages8
JournalCritical Reviews in Oncology/Hematology
Volume132
DOIs
Publication statusPublished - Dec 1 2018

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Esophagogastric Junction
Neoplasms
Ontario
Esophageal Neoplasms
General Practitioners
Physical Examination
Therapeutics
Guidelines
Carcinoma
Delivery of Health Care
Physicians

Keywords

  • Esophageal Cancer
  • Gastroesophageal junction cancer
  • Multimodal therapy
  • Surgical oncology

ASJC Scopus subject areas

  • Hematology
  • Oncology

Cite this

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abstract = "Cancer of the esophagus and of gastroesophageal junction can be cured, even if with lacking cure rate. Different approaches have been developed, mostly when carcinoma has loco-regional pattern. Multimodality therapy showed a survival rate superior than 10{\%} if compared to a single approach. This is a systematic review, carried to assess the following matters: Which therapeutic opportunities are available? Who could benefit of them? Which adverse reactions could possibly verify? How can physicians definitely choose the proper strategy? Which is the role of surgery? We mean to give either General Practitioner or specialists clear and efficient updates about current treatment of this tumour, starting from physical examination. Four eminent guidelines were consulted for our study: Cancer Care Ontario's Program in Evidence-Based Care, NCCN, Belgian Health Care Knowledge Centre and Esmo.",
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author = "Antonio Chiappa and Bruno Andreoni and Renzo Dionigi and Lorenzo Spaggiari and Diego Foschi and Gianluca Polvani and Roberto Orecchia and Nicola Fazio and Gabriella Pravettoni and Cossu, {Maria Laura} and Domenico Galetta and Marco Venturino and Carlo Ferrari and Lorenzo Macone and Cristiano Crosta and Bernardo Bonanni and Roberto Biffi",
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T1 - A rationale multidisciplinary approach for treatment of esophageal and gastroesophageal junction cancer

T2 - Accurate review of management and perspectives

AU - Chiappa, Antonio

AU - Andreoni, Bruno

AU - Dionigi, Renzo

AU - Spaggiari, Lorenzo

AU - Foschi, Diego

AU - Polvani, Gianluca

AU - Orecchia, Roberto

AU - Fazio, Nicola

AU - Pravettoni, Gabriella

AU - Cossu, Maria Laura

AU - Galetta, Domenico

AU - Venturino, Marco

AU - Ferrari, Carlo

AU - Macone, Lorenzo

AU - Crosta, Cristiano

AU - Bonanni, Bernardo

AU - Biffi, Roberto

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Cancer of the esophagus and of gastroesophageal junction can be cured, even if with lacking cure rate. Different approaches have been developed, mostly when carcinoma has loco-regional pattern. Multimodality therapy showed a survival rate superior than 10% if compared to a single approach. This is a systematic review, carried to assess the following matters: Which therapeutic opportunities are available? Who could benefit of them? Which adverse reactions could possibly verify? How can physicians definitely choose the proper strategy? Which is the role of surgery? We mean to give either General Practitioner or specialists clear and efficient updates about current treatment of this tumour, starting from physical examination. Four eminent guidelines were consulted for our study: Cancer Care Ontario's Program in Evidence-Based Care, NCCN, Belgian Health Care Knowledge Centre and Esmo.

AB - Cancer of the esophagus and of gastroesophageal junction can be cured, even if with lacking cure rate. Different approaches have been developed, mostly when carcinoma has loco-regional pattern. Multimodality therapy showed a survival rate superior than 10% if compared to a single approach. This is a systematic review, carried to assess the following matters: Which therapeutic opportunities are available? Who could benefit of them? Which adverse reactions could possibly verify? How can physicians definitely choose the proper strategy? Which is the role of surgery? We mean to give either General Practitioner or specialists clear and efficient updates about current treatment of this tumour, starting from physical examination. Four eminent guidelines were consulted for our study: Cancer Care Ontario's Program in Evidence-Based Care, NCCN, Belgian Health Care Knowledge Centre and Esmo.

KW - Esophageal Cancer

KW - Gastroesophageal junction cancer

KW - Multimodal therapy

KW - Surgical oncology

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