A rationale multidisciplinary approach for treatment of esophageal and gastroesophageal junction cancer: Accurate review of management and perspectives

A. Chiappa, B. Andreoni, R. Dionigi, L. Spaggiari, D. Foschi, G. Polvani, R. Orecchia, N. Fazio, G. Pravettoni, M.L. Cossu, D. Galetta, M. Venturino, Carlo Ferrari, Lorenzo Macone, C. Crosta, B. Bonanni, R. Biffi

Research output: Contribution to journalArticle

Abstract

Cancer of the esophagus and of gastroesophageal junction can be cured, even if with lacking cure rate. Different approaches have been developed, mostly when carcinoma has loco-regional pattern. Multimodality therapy showed a survival rate superior than 10% if compared to a single approach. This is a systematic review, carried to assess the following matters: Which therapeutic opportunities are available? Who could benefit of them? Which adverse reactions could possibly verify? How can physicians definitely choose the proper strategy? Which is the role of surgery? We mean to give either General Practitioner or specialists clear and efficient updates about current treatment of this tumour, starting from physical examination. Four eminent guidelines were consulted for our study: Cancer Care Ontario's Program in Evidence-Based Care, NCCN, Belgian Health Care Knowledge Centre and Esmo. © 2018 Elsevier B.V.
Original languageEnglish
Pages (from-to)161-168
Number of pages8
JournalCritical Reviews in Oncology/Hematology
Volume132
DOIs
Publication statusPublished - 2018

Keywords

  • Esophageal Cancer
  • Gastroesophageal junction cancer
  • Multimodal therapy
  • Surgical oncology
  • antineoplastic agent
  • Belgium
  • blood toxicity
  • cancer adjuvant therapy
  • cancer surgery
  • cancer survival
  • chemoradiotherapy
  • clinical decision making
  • clinical practice
  • esophagus cancer
  • evidence based practice
  • gastroesophageal junction
  • gastrointestinal toxicity
  • general practitioner
  • human
  • medical specialist
  • multimodality cancer therapy
  • neoadjuvant chemotherapy
  • neoadjuvant therapy
  • Ontario
  • overall survival
  • patient care
  • perioperative period
  • physical examination
  • physician
  • postoperative complication
  • practice guideline
  • preoperative period
  • randomized controlled trial (topic)
  • Review
  • salvage therapy
  • stomach cancer
  • systematic review
  • disease management
  • esophagus tumor
  • pathology
  • prognosis
  • stomach tumor
  • Combined Modality Therapy
  • Disease Management
  • Esophageal Neoplasms
  • Esophagogastric Junction
  • Humans
  • Prognosis
  • Stomach Neoplasms

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