A renal cancer with intermediate characteristics between collecting (Bellini) duct carcinoma and urothelial carcinoma: Case report and review of the literature

Umberto Maestroni, Stefania Ferretti, Francesco Dinale, Elisabetta Froio, Francesco Paolo Pilato, Matteo Ciuffreda, Massimo Mellissari, Pietro Cortellini

Research output: Contribution to journalArticle

Abstract

Collecting duct carcinoma of the kidney is a rare and aggressive neoplasm of the distal collecting tube, often metastatic at the time of the diagnosis, for which there is no established therapy. We herein describe the case of a 65-year-old man with a renal cancer with a particular immunohistochemical pattern and pathologic aspect. The lesion was diagnosed as a tumor borderline between a urothelial carcinoma with intraductal spreading and a collecting duct carcinoma with calyceal and pelvic spreading. The patient is disease-free 11 months after diagnosis, after radical surgery with adjuvant chemotherapy (carboplatine and gemcitabine) and radiotherapy of a local recurrence. Owing to the common embryologic origin of collecting duct and transitional urothelial cells, several authors have reported an association between collecting duct carcinoma and urothelial cancer. The literature is reviewed to evaluate drugs active against urothelial cancer (like ifosfamide, paclitaxel, carboplatin and gemcitabine). This field should be investigated in the future, in the framework of a neoadjuvant or adjuvant chemotherapy able to support radical surgery for local and advanced collecting duct carcinoma.

Original languageEnglish
Pages (from-to)545-548
Number of pages4
JournalTumori
Volume92
Issue number6
Publication statusPublished - Nov 2006

Keywords

  • Bellini carcinoma
  • Chemotherapy
  • Collecting duct carcinoma
  • Urothelial cancer

ASJC Scopus subject areas

  • Cancer Research

Fingerprint Dive into the research topics of 'A renal cancer with intermediate characteristics between collecting (Bellini) duct carcinoma and urothelial carcinoma: Case report and review of the literature'. Together they form a unique fingerprint.

  • Cite this

    Maestroni, U., Ferretti, S., Dinale, F., Froio, E., Pilato, F. P., Ciuffreda, M., Mellissari, M., & Cortellini, P. (2006). A renal cancer with intermediate characteristics between collecting (Bellini) duct carcinoma and urothelial carcinoma: Case report and review of the literature. Tumori, 92(6), 545-548.