A review of the concept of circulatory bioassist focused on the "new" demand dynamic cardiomyoplasty: The renewal of dynamic cardiomyoplasty?

Gianluca Rigatelli, Ugo Carraro, Mario Barbiero, Roberto Riccardi, Franco Cobelli, Marzio Gemelli, Giorgio Rigatelli

Research output: Contribution to journalArticlepeer-review

Abstract

After the initial enthusiasm, the dynamic cardiomyoplasty lost its reputation owing to the poor long-term results, caused by the muscular degeneration subsequent to chronic continuous electrical stimulation of the latissimus dorsi. An activity-rest stimulation protocol that avoids full transformation of the skeletal muscle, maintaining muscular properties over time, has been successfully tried. This "demand" stimulation protocol showed in humans good results improving NYHA class, ejection fraction value, and survival. The discussion about the capability of this and a unique kind of cardiocirculatory bioassist is due to be reopened. In fact, heart transplant, percutaneous circulatory-supporting device, multisites stimulation therapy, and total artificial heart have some drawbacks, one of which is the economic cost. In developing countries the more economic demand dynamic cardiomyoplasty may still play a role.

Original languageEnglish
Pages (from-to)301-306
Number of pages6
JournalAngiology
Volume54
Issue number3
Publication statusPublished - May 2003

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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