I geni di suscettibilità all'infarto: Una revisione della letteratura

Translated title of the contribution: A review on the susceptibility genes of myocardial infarction

B. D. Chiodini, S. Barlera, M. G. Franzosi, G. Tognoni

Research output: Contribution to journalArticle

Abstract

The investigation on the susceptibility genes of myocardial infarction has initiated substantially in the last 20 years. Most efforts have been mainly addressed to identify and evaluate genes involved in those systems already suspected to be implicated in the pathogenesis of coronary heart disease. Principal examples are lipid metabolism, coagulation and fibrinolytic systems, membrane receptors of platelets, levels of plasma homocysteine and vascular tone. Therefore up to now, the identification of the genetic factors of myocardial infarction has been carried out through case-control association studies employing a "candidate gene" approach. This method has often led to controversial results, usually difficult to compare. This is an attempt to provide a progress report on the principal susceptibility genes of coronary heart disease.

Translated title of the contributionA review on the susceptibility genes of myocardial infarction
Original languageItalian
Pages (from-to)935-944
Number of pages10
JournalItalian Heart Journal Supplement
Volume2
Issue number9
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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  • Cite this

    Chiodini, B. D., Barlera, S., Franzosi, M. G., & Tognoni, G. (2001). I geni di suscettibilità all'infarto: Una revisione della letteratura. Italian Heart Journal Supplement, 2(9), 935-944.