A Risk Score and a Flowchart for Liver Retransplantation

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Abstract

Rates of overall graft survival after liver retransplantation (RETX) are still 20% lower than those after primary liver transplantation (TX). On the basis of previous mathematical approaches from other authors who tried to identify prognostic variables for survival and prognostic risk scores for liver RETX, we studied 12 categorical and 17 continuous variables from the donor, the recipient, and the surgical procedure, among patients who underwent liver retransplantation. Data were retrieved in a retrospective study over the last 12 years, in order to overcome the possible gap of other series that often included RETX performed many years ago. We considered 394 consecutive cadaveric liver TXs in adult patients, namely, 351 primary TXs and 43 RETXs. Using multivariate logistic regression, we calculated the following equation for 1-year risk of death for patients undergoing liver RETX: log(Odds) = -4.81 + 2.23 × Recipient Sex + 1.86 × Donor Age + 1.60 × MELD Score (where: Recipient Sex: F = 0, M = 1; Donor Age (years):

Original languageEnglish
Pages (from-to)1956-1960
Number of pages5
JournalTransplantation Proceedings
Volume40
Issue number6
DOIs
Publication statusPublished - Jul 2008

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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