Abstract
The Paced Auditory Serial Addition Test (PASAT), most used neuropsychological test in people with multiple sclerosis (pwMS), is available as PASAT-3 and more difficult PASAT-2. We determined PASAT performance in 105 pwMS and 105 matched controls and assessed the utility of a shortened PASAT-3 version. Qualitative and quantitative analyses were performed, the latter involving assessment of dyads (two consecutive correct responses) and singles (correct response between two omitted responses). Based on provisional results we then calculated the sensitivity of the first 20 items of PASAT-3 in relation to the full version. Mean PASAT-2 and 3 total score, dyads and singles differed significantly (P≤0.0002) in pwMS and controls, due to more omissions in pwMS, number and type of incorrect answers did not differ. Differences between pwMS and controls were highly significant for the first 50, 40, 30 and 20 responses of the PASAT-3. The sensitivity of the first 20 items of PASAT-3 was 87% (95% Cl 0.70-1.00). PASAT-3 and PASAT-2 effectively discriminate pwMS from controls. Use of the first 20 items of PASAT-3 appears as a highly useful PASAT-3 version as it retains the discriminative value and sensitivity of the full version yet is quicker to administer and less demanding.
| Original language | English |
|---|---|
| Pages (from-to) | 1020-1025 |
| Number of pages | 6 |
| Journal | Multiple Sclerosis Journal |
| Volume | 13 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Sep 2007 |
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Keywords
- Cognitive test
- Multiple sclerosis
- Multiple sclerosis functional composite
- Normal controls
- PASAT
ASJC Scopus subject areas
- Clinical Neurology
Cite this
A shortened version of PASAT-3 is feasible. / Solari, Alessandra; Motta, A.; Radice, D.; Mendozzi, L.
In: Multiple Sclerosis Journal, Vol. 13, No. 8, 09.2007, p. 1020-1025.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A shortened version of PASAT-3 is feasible
AU - Solari, Alessandra
AU - Motta, A.
AU - Radice, D.
AU - Mendozzi, L.
PY - 2007/9
Y1 - 2007/9
N2 - The Paced Auditory Serial Addition Test (PASAT), most used neuropsychological test in people with multiple sclerosis (pwMS), is available as PASAT-3 and more difficult PASAT-2. We determined PASAT performance in 105 pwMS and 105 matched controls and assessed the utility of a shortened PASAT-3 version. Qualitative and quantitative analyses were performed, the latter involving assessment of dyads (two consecutive correct responses) and singles (correct response between two omitted responses). Based on provisional results we then calculated the sensitivity of the first 20 items of PASAT-3 in relation to the full version. Mean PASAT-2 and 3 total score, dyads and singles differed significantly (P≤0.0002) in pwMS and controls, due to more omissions in pwMS, number and type of incorrect answers did not differ. Differences between pwMS and controls were highly significant for the first 50, 40, 30 and 20 responses of the PASAT-3. The sensitivity of the first 20 items of PASAT-3 was 87% (95% Cl 0.70-1.00). PASAT-3 and PASAT-2 effectively discriminate pwMS from controls. Use of the first 20 items of PASAT-3 appears as a highly useful PASAT-3 version as it retains the discriminative value and sensitivity of the full version yet is quicker to administer and less demanding.
AB - The Paced Auditory Serial Addition Test (PASAT), most used neuropsychological test in people with multiple sclerosis (pwMS), is available as PASAT-3 and more difficult PASAT-2. We determined PASAT performance in 105 pwMS and 105 matched controls and assessed the utility of a shortened PASAT-3 version. Qualitative and quantitative analyses were performed, the latter involving assessment of dyads (two consecutive correct responses) and singles (correct response between two omitted responses). Based on provisional results we then calculated the sensitivity of the first 20 items of PASAT-3 in relation to the full version. Mean PASAT-2 and 3 total score, dyads and singles differed significantly (P≤0.0002) in pwMS and controls, due to more omissions in pwMS, number and type of incorrect answers did not differ. Differences between pwMS and controls were highly significant for the first 50, 40, 30 and 20 responses of the PASAT-3. The sensitivity of the first 20 items of PASAT-3 was 87% (95% Cl 0.70-1.00). PASAT-3 and PASAT-2 effectively discriminate pwMS from controls. Use of the first 20 items of PASAT-3 appears as a highly useful PASAT-3 version as it retains the discriminative value and sensitivity of the full version yet is quicker to administer and less demanding.
KW - Cognitive test
KW - Multiple sclerosis
KW - Multiple sclerosis functional composite
KW - Normal controls
KW - PASAT
UR - http://www.scopus.com/inward/record.url?scp=38449101243&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38449101243&partnerID=8YFLogxK
U2 - 10.1177/1352458507077619
DO - 10.1177/1352458507077619
M3 - Article
VL - 13
SP - 1020
EP - 1025
JO - Multiple Sclerosis
JF - Multiple Sclerosis
SN - 1352-4585
IS - 8
ER -