A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients

G. Leonetti; A. Rappelli; S. Omboni; R. Ansuini; N. Acquarone; E. Antonucci; M. Campanini; E. Paracchini; L. Celegon; F. Lazzari; M. Crippa; D. Caruso; M. D'Avino; M. Di Biase; V. Manuppelli; P. L. Pellegrino; N. Etna; C. Fiorentini; S. Lucreziotti; F. Galetta; F. Franzoni; R. Femia; R. Giovannetti; A. Auteri; F. Bruni; A. Leo; L. Lonati; G. C. Magnaghi; P. Sensale; O. Maiolica; C. Malinverni; S. Mangiameli; R. Cardillo; A. Antonelli; L. Mazzotta; R. Nami; D. P. Salvo; U. Pezzotti; G. Monti; P. Novati; R. Furlan; F. Perego; S. Pede; C. Pico; A. Renna; A. Margonato; R. Pizzetti; D. Prinzi; D. Smimmo; G. De Cicco; G. Napolitano; M. Reynaud; M. Piccoli; G. Cipollari; P. L. Saccà; U. Oliviero; E. L. Ettari; F. Scanferla; G. Rosato; F. Siano; G. M. Cianciucci; M. R. Pagliuca; A. Santucci; C. Ferri; G. B. Desideri; O. Zingaretti

doi:10.1080/08038020510046689

A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients

G. Leonetti, A. Rappelli, S. Omboni, R. Ansuini, N. Acquarone, E. Antonucci, M. Campanini, E. Paracchini, L. Celegon, F. Lazzari, M. Crippa, D. Caruso, M. D'Avino, M. Di Biase, V. Manuppelli, P. L. Pellegrino, N. Etna, C. Fiorentini, S. Lucreziotti, F. GalettaF. Franzoni, R. Femia, R. Giovannetti, A. Auteri, F. Bruni, A. Leo, L. Lonati, G. C. Magnaghi, P. Sensale, O. Maiolica, C. Malinverni, S. Mangiameli, R. Cardillo, A. Antonelli, L. Mazzotta, R. Nami, D. P. Salvo, U. Pezzotti, G. Monti, P. Novati, R. Furlan, F. Perego, S. Pede, C. Pico, A. Renna, A. Margonato, R. Pizzetti, D. Prinzi, D. Smimmo, G. De Cicco, G. Napolitano, M. Reynaud, M. Piccoli, G. Cipollari, P. L. Saccà, U. Oliviero, E. L. Ettari, F. Scanferla, G. Rosato, F. Siano, G. M. Cianciucci, M. R. Pagliuca, A. Santucci, C. Ferri, G. B. Desideri, O. Zingaretti

Research output: Contribution to journal › Article › peer-review

Abstract

Objective. To compare the antihypertensive effect of treatment with zofenopril vs candesartan by office and ambulatory blood pressure (BP). Design and methods. Following a 2-week wash-out from previous treatment, 236 grade I-II primary hypertensive patients were randomized double-blind to 12 weeks treatment with zofenopril 30 mg or candesartan 8 mg od. After 4 weeks, treatment was doubled in responder non-normalized (office systolic BP≥140 mmHg and office diastolic BP reduction ≥10 mmHg) or non-responder patients (office systolic BP≥140 mmHg and office diastolic BP reduction

Original language	English
Pages (from-to)	18-26
Number of pages	9
Journal	Blood Pressure
Volume	15
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1080/08038020510046689
Publication status	Published - Mar 2006

Keywords

Ambulatory blood pressure monitoring
Candesartan
Primary hypertension
Smoothness index
Trough-to-peak ratio
Zofenopril

ASJC Scopus subject areas

Internal Medicine
Cardiology and Cardiovascular Medicine

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10.1080/08038020510046689

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Leonetti, G., Rappelli, A., Omboni, S., Ansuini, R., Acquarone, N., Antonucci, E., Campanini, M., Paracchini, E., Celegon, L., Lazzari, F., Crippa, M., Caruso, D., D'Avino, M., Di Biase, M., Manuppelli, V., Pellegrino, P. L., Etna, N., Fiorentini, C., Lucreziotti, S., ... Zingaretti, O. (2006). A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients. Blood Pressure, 15(SUPPL. 1), 18-26. https://doi.org/10.1080/08038020510046689

Leonetti, G, Rappelli, A, Omboni, S, Ansuini, R, Acquarone, N, Antonucci, E, Campanini, M, Paracchini, E, Celegon, L, Lazzari, F, Crippa, M, Caruso, D, D'Avino, M, Di Biase, M, Manuppelli, V, Pellegrino, PL, Etna, N, Fiorentini, C, Lucreziotti, S, Galetta, F, Franzoni, F, Femia, R, Giovannetti, R, Auteri, A, Bruni, F, Leo, A, Lonati, L, Magnaghi, GC, Sensale, P, Maiolica, O, Malinverni, C, Mangiameli, S, Cardillo, R, Antonelli, A, Mazzotta, L, Nami, R, Salvo, DP, Pezzotti, U, Monti, G, Novati, P, Furlan, R, Perego, F, Pede, S, Pico, C, Renna, A, Margonato, A, Pizzetti, R, Prinzi, D, Smimmo, D, De Cicco, G, Napolitano, G, Reynaud, M, Piccoli, M, Cipollari, G, Saccà, PL, Oliviero, U, Ettari, EL, Scanferla, F, Rosato, G, Siano, F, Cianciucci, GM, Pagliuca, MR, Santucci, A, Ferri, C, Desideri, GB & Zingaretti, O 2006, 'A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients', Blood Pressure, vol. 15, no. SUPPL. 1, pp. 18-26. https://doi.org/10.1080/08038020510046689

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title = "A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients",

abstract = "Objective. To compare the antihypertensive effect of treatment with zofenopril vs candesartan by office and ambulatory blood pressure (BP). Design and methods. Following a 2-week wash-out from previous treatment, 236 grade I-II primary hypertensive patients were randomized double-blind to 12 weeks treatment with zofenopril 30 mg or candesartan 8 mg od. After 4 weeks, treatment was doubled in responder non-normalized (office systolic BP≥140 mmHg and office diastolic BP reduction ≥10 mmHg) or non-responder patients (office systolic BP≥140 mmHg and office diastolic BP reduction ",

keywords = "Ambulatory blood pressure monitoring, Candesartan, Primary hypertension, Smoothness index, Trough-to-peak ratio, Zofenopril",

author = "G. Leonetti and A. Rappelli and S. Omboni and R. Ansuini and N. Acquarone and E. Antonucci and M. Campanini and E. Paracchini and L. Celegon and F. Lazzari and M. Crippa and D. Caruso and M. D'Avino and {Di Biase}, M. and V. Manuppelli and Pellegrino, {P. L.} and N. Etna and C. Fiorentini and S. Lucreziotti and F. Galetta and F. Franzoni and R. Femia and R. Giovannetti and A. Auteri and F. Bruni and A. Leo and L. Lonati and Magnaghi, {G. C.} and P. Sensale and O. Maiolica and C. Malinverni and S. Mangiameli and R. Cardillo and A. Antonelli and L. Mazzotta and R. Nami and Salvo, {D. P.} and U. Pezzotti and G. Monti and P. Novati and R. Furlan and F. Perego and S. Pede and C. Pico and A. Renna and A. Margonato and R. Pizzetti and D. Prinzi and D. Smimmo and {De Cicco}, G. and G. Napolitano and M. Reynaud and M. Piccoli and G. Cipollari and Sacc{\`a}, {P. L.} and U. Oliviero and Ettari, {E. L.} and F. Scanferla and G. Rosato and F. Siano and Cianciucci, {G. M.} and Pagliuca, {M. R.} and A. Santucci and C. Ferri and Desideri, {G. B.} and O. Zingaretti",

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doi = "10.1080/08038020510046689",

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AU - Leonetti, G.

AU - Rappelli, A.

AU - Omboni, S.

AU - Ansuini, R.

AU - Acquarone, N.

AU - Antonucci, E.

AU - Campanini, M.

AU - Paracchini, E.

AU - Celegon, L.

AU - Lazzari, F.

AU - Crippa, M.

AU - Caruso, D.

AU - D'Avino, M.

AU - Di Biase, M.

AU - Manuppelli, V.

AU - Pellegrino, P. L.

AU - Etna, N.

AU - Fiorentini, C.

AU - Lucreziotti, S.

AU - Galetta, F.

AU - Franzoni, F.

AU - Femia, R.

AU - Giovannetti, R.

AU - Auteri, A.

AU - Bruni, F.

AU - Leo, A.

AU - Lonati, L.

AU - Magnaghi, G. C.

AU - Sensale, P.

AU - Maiolica, O.

AU - Malinverni, C.

AU - Mangiameli, S.

AU - Cardillo, R.

AU - Antonelli, A.

AU - Mazzotta, L.

AU - Nami, R.

AU - Salvo, D. P.

AU - Pezzotti, U.

AU - Monti, G.

AU - Novati, P.

AU - Furlan, R.

AU - Perego, F.

AU - Pede, S.

AU - Pico, C.

AU - Renna, A.

AU - Margonato, A.

AU - Pizzetti, R.

AU - Prinzi, D.

AU - Smimmo, D.

AU - De Cicco, G.

AU - Napolitano, G.

AU - Reynaud, M.

AU - Piccoli, M.

AU - Cipollari, G.

AU - Saccà, P. L.

AU - Oliviero, U.

AU - Ettari, E. L.

AU - Scanferla, F.

AU - Rosato, G.

AU - Siano, F.

AU - Cianciucci, G. M.

AU - Pagliuca, M. R.

AU - Santucci, A.

AU - Ferri, C.

AU - Desideri, G. B.

AU - Zingaretti, O.

PY - 2006/3

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N2 - Objective. To compare the antihypertensive effect of treatment with zofenopril vs candesartan by office and ambulatory blood pressure (BP). Design and methods. Following a 2-week wash-out from previous treatment, 236 grade I-II primary hypertensive patients were randomized double-blind to 12 weeks treatment with zofenopril 30 mg or candesartan 8 mg od. After 4 weeks, treatment was doubled in responder non-normalized (office systolic BP≥140 mmHg and office diastolic BP reduction ≥10 mmHg) or non-responder patients (office systolic BP≥140 mmHg and office diastolic BP reduction

AB - Objective. To compare the antihypertensive effect of treatment with zofenopril vs candesartan by office and ambulatory blood pressure (BP). Design and methods. Following a 2-week wash-out from previous treatment, 236 grade I-II primary hypertensive patients were randomized double-blind to 12 weeks treatment with zofenopril 30 mg or candesartan 8 mg od. After 4 weeks, treatment was doubled in responder non-normalized (office systolic BP≥140 mmHg and office diastolic BP reduction ≥10 mmHg) or non-responder patients (office systolic BP≥140 mmHg and office diastolic BP reduction

KW - Ambulatory blood pressure monitoring

KW - Candesartan

KW - Primary hypertension

KW - Smoothness index

KW - Trough-to-peak ratio

KW - Zofenopril

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JO - Blood Pressure

JF - Blood Pressure

SN - 0803-7051

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ER -

A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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