A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients

G. Leonetti; A. Rappelli; S. Omboni; R. Ansuini; N. Acquarone; E. Antonucci; M. Campanini; E. Paracchini; L. Celegon; F. Lazzari; M. Crippa; D. Caruso; M. D'Avino; M. Di Biase; V. Manuppelli; P. L. Pellegrino; N. Etna; C. Fiorentini; S. Lucreziotti; F. Galetta; F. Franzoni; R. Femia; R. Giovannetti; A. Auteri; F. Bruni; A. Leo; L. Lonati; G. C. Magnaghi; P. Sensale; O. Maiolica; C. Malinverni; S. Mangiameli; R. Cardillo; A. Antonelli; L. Mazzotta; R. Nami; D. P. Salvo; U. Pezzotti; G. Monti; P. Novati; R. Furlan; F. Perego; S. Pede; C. Pico; A. Renna; A. Margonato; R. Pizzetti; D. Prinzi; D. Smimmo; G. De Cicco; G. Napolitano; M. Reynaud; M. Piccoli; G. Cipollari; P. L. Saccà; U. Oliviero; E. L. Ettari; F. Scanferla; G. Rosato; F. Siano; G. M. Cianciucci; M. R. Pagliuca; A. Santucci; C. Ferri; G. B. Desideri; O. Zingaretti

doi:10.1080/08038020510046689

A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients

G. Leonetti, A. Rappelli, S. Omboni, R. Ansuini, N. Acquarone, E. Antonucci, M. Campanini, E. Paracchini, L. Celegon, F. Lazzari, M. Crippa, D. Caruso, M. D'Avino, M. Di Biase, V. Manuppelli, P. L. Pellegrino, N. Etna, C. Fiorentini, S. Lucreziotti, F. GalettaF. Franzoni, R. Femia, R. Giovannetti, A. Auteri, F. Bruni, A. Leo, L. Lonati, G. C. Magnaghi, P. Sensale, O. Maiolica, C. Malinverni, S. Mangiameli, R. Cardillo, A. Antonelli, L. Mazzotta, R. Nami, D. P. Salvo, U. Pezzotti, G. Monti, P. Novati, R. Furlan, F. Perego, S. Pede, C. Pico, A. Renna, A. Margonato, R. Pizzetti, D. Prinzi, D. Smimmo, G. De Cicco, G. Napolitano, M. Reynaud, M. Piccoli, G. Cipollari, P. L. Saccà, U. Oliviero, E. L. Ettari, F. Scanferla, G. Rosato, F. Siano, G. M. Cianciucci, M. R. Pagliuca, A. Santucci, C. Ferri, G. B. Desideri, O. Zingaretti

Research output: Contribution to journal › Article

Abstract

Objective. To compare the antihypertensive effect of treatment with zofenopril vs candesartan by office and ambulatory blood pressure (BP). Design and methods. Following a 2-week wash-out from previous treatment, 236 grade I-II primary hypertensive patients were randomized double-blind to 12 weeks treatment with zofenopril 30 mg or candesartan 8 mg od. After 4 weeks, treatment was doubled in responder non-normalized (office systolic BP≥140 mmHg and office diastolic BP reduction ≥10 mmHg) or non-responder patients (office systolic BP≥140 mmHg and office diastolic BP reduction

Original language	English
Pages (from-to)	18-26
Number of pages	9
Journal	Blood Pressure
Volume	15
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1080/08038020510046689
Publication status	Published - Mar 2006

Keywords

Ambulatory blood pressure monitoring
Candesartan
Primary hypertension
Smoothness index
Trough-to-peak ratio
Zofenopril

ASJC Scopus subject areas

Internal Medicine
Cardiology and Cardiovascular Medicine

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10.1080/08038020510046689

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Leonetti, G., Rappelli, A., Omboni, S., Ansuini, R., Acquarone, N., Antonucci, E., Campanini, M., Paracchini, E., Celegon, L., Lazzari, F., Crippa, M., Caruso, D., D'Avino, M., Di Biase, M., Manuppelli, V., Pellegrino, P. L., Etna, N., Fiorentini, C., Lucreziotti, S., ... Zingaretti, O. (2006). A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients. Blood Pressure, 15(SUPPL. 1), 18-26. https://doi.org/10.1080/08038020510046689

A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients. / Leonetti, G.; Rappelli, A.; Omboni, S.; Ansuini, R.; Acquarone, N.; Antonucci, E.; Campanini, M.; Paracchini, E.; Celegon, L.; Lazzari, F.; Crippa, M.; Caruso, D.; D'Avino, M.; Di Biase, M.; Manuppelli, V.; Pellegrino, P. L.; Etna, N.; Fiorentini, C.; Lucreziotti, S.; Galetta, F.; Franzoni, F.; Femia, R.; Giovannetti, R.; Auteri, A.; Bruni, F.; Leo, A.; Lonati, L.; Magnaghi, G. C.; Sensale, P.; Maiolica, O.; Malinverni, C.; Mangiameli, S.; Cardillo, R.; Antonelli, A.; Mazzotta, L.; Nami, R.; Salvo, D. P.; Pezzotti, U.; Monti, G.; Novati, P.; Furlan, R.; Perego, F.; Pede, S.; Pico, C.; Renna, A.; Margonato, A.; Pizzetti, R.; Prinzi, D.; Smimmo, D.; De Cicco, G.; Napolitano, G.; Reynaud, M.; Piccoli, M.; Cipollari, G.; Saccà, P. L.; Oliviero, U.; Ettari, E. L.; Scanferla, F.; Rosato, G.; Siano, F.; Cianciucci, G. M.; Pagliuca, M. R.; Santucci, A.; Ferri, C.; Desideri, G. B.; Zingaretti, O.

In: Blood Pressure, Vol. 15, No. SUPPL. 1, 03.2006, p. 18-26.

Research output: Contribution to journal › Article

Leonetti, G, Rappelli, A, Omboni, S, Ansuini, R, Acquarone, N, Antonucci, E, Campanini, M, Paracchini, E, Celegon, L, Lazzari, F, Crippa, M, Caruso, D, D'Avino, M, Di Biase, M, Manuppelli, V, Pellegrino, PL, Etna, N, Fiorentini, C, Lucreziotti, S, Galetta, F, Franzoni, F, Femia, R, Giovannetti, R, Auteri, A, Bruni, F, Leo, A, Lonati, L, Magnaghi, GC, Sensale, P, Maiolica, O, Malinverni, C, Mangiameli, S, Cardillo, R, Antonelli, A, Mazzotta, L, Nami, R, Salvo, DP, Pezzotti, U, Monti, G, Novati, P, Furlan, R, Perego, F, Pede, S, Pico, C, Renna, A, Margonato, A, Pizzetti, R, Prinzi, D, Smimmo, D, De Cicco, G, Napolitano, G, Reynaud, M, Piccoli, M, Cipollari, G, Saccà, PL, Oliviero, U, Ettari, EL, Scanferla, F, Rosato, G, Siano, F, Cianciucci, GM, Pagliuca, MR, Santucci, A, Ferri, C, Desideri, GB & Zingaretti, O 2006, 'A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients', Blood Pressure, vol. 15, no. SUPPL. 1, pp. 18-26. https://doi.org/10.1080/08038020510046689

Leonetti, G. ; Rappelli, A. ; Omboni, S. ; Ansuini, R. ; Acquarone, N. ; Antonucci, E. ; Campanini, M. ; Paracchini, E. ; Celegon, L. ; Lazzari, F. ; Crippa, M. ; Caruso, D. ; D'Avino, M. ; Di Biase, M. ; Manuppelli, V. ; Pellegrino, P. L. ; Etna, N. ; Fiorentini, C. ; Lucreziotti, S. ; Galetta, F. ; Franzoni, F. ; Femia, R. ; Giovannetti, R. ; Auteri, A. ; Bruni, F. ; Leo, A. ; Lonati, L. ; Magnaghi, G. C. ; Sensale, P. ; Maiolica, O. ; Malinverni, C. ; Mangiameli, S. ; Cardillo, R. ; Antonelli, A. ; Mazzotta, L. ; Nami, R. ; Salvo, D. P. ; Pezzotti, U. ; Monti, G. ; Novati, P. ; Furlan, R. ; Perego, F. ; Pede, S. ; Pico, C. ; Renna, A. ; Margonato, A. ; Pizzetti, R. ; Prinzi, D. ; Smimmo, D. ; De Cicco, G. ; Napolitano, G. ; Reynaud, M. ; Piccoli, M. ; Cipollari, G. ; Saccà, P. L. ; Oliviero, U. ; Ettari, E. L. ; Scanferla, F. ; Rosato, G. ; Siano, F. ; Cianciucci, G. M. ; Pagliuca, M. R. ; Santucci, A. ; Ferri, C. ; Desideri, G. B. ; Zingaretti, O. / A similar 24-h blood pressure control is obtained by zofenopril and candesartan in primary hypertensive patients. In: Blood Pressure. 2006 ; Vol. 15, No. SUPPL. 1. pp. 18-26.

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abstract = "Objective. To compare the antihypertensive effect of treatment with zofenopril vs candesartan by office and ambulatory blood pressure (BP). Design and methods. Following a 2-week wash-out from previous treatment, 236 grade I-II primary hypertensive patients were randomized double-blind to 12 weeks treatment with zofenopril 30 mg or candesartan 8 mg od. After 4 weeks, treatment was doubled in responder non-normalized (office systolic BP≥140 mmHg and office diastolic BP reduction ≥10 mmHg) or non-responder patients (office systolic BP≥140 mmHg and office diastolic BP reduction ",

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AU - Rappelli, A.

AU - Omboni, S.

AU - Ansuini, R.

AU - Acquarone, N.

AU - Antonucci, E.

AU - Campanini, M.

AU - Paracchini, E.

AU - Celegon, L.

AU - Lazzari, F.

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AU - Caruso, D.

AU - D'Avino, M.

AU - Di Biase, M.

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AU - Lucreziotti, S.

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AU - Franzoni, F.

AU - Femia, R.

AU - Giovannetti, R.

AU - Auteri, A.

AU - Bruni, F.

AU - Leo, A.

AU - Lonati, L.

AU - Magnaghi, G. C.

AU - Sensale, P.

AU - Maiolica, O.

AU - Malinverni, C.

AU - Mangiameli, S.

AU - Cardillo, R.

AU - Antonelli, A.

AU - Mazzotta, L.

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AU - Salvo, D. P.

AU - Pezzotti, U.

AU - Monti, G.

AU - Novati, P.

AU - Furlan, R.

AU - Perego, F.

AU - Pede, S.

AU - Pico, C.

AU - Renna, A.

AU - Margonato, A.

AU - Pizzetti, R.

AU - Prinzi, D.

AU - Smimmo, D.

AU - De Cicco, G.

AU - Napolitano, G.

AU - Reynaud, M.

AU - Piccoli, M.

AU - Cipollari, G.

AU - Saccà, P. L.

AU - Oliviero, U.

AU - Ettari, E. L.

AU - Scanferla, F.

AU - Rosato, G.

AU - Siano, F.

AU - Cianciucci, G. M.

AU - Pagliuca, M. R.

AU - Santucci, A.

AU - Ferri, C.

AU - Desideri, G. B.

AU - Zingaretti, O.

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KW - Ambulatory blood pressure monitoring

KW - Candesartan

KW - Primary hypertension

KW - Smoothness index

KW - Trough-to-peak ratio

KW - Zofenopril

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