Abstract
Objective. To compare the antihypertensive effect of treatment with zofenopril vs candesartan by office and ambulatory blood pressure (BP). Design and methods. Following a 2-week wash-out from previous treatment, 236 grade I-II primary hypertensive patients were randomized double-blind to 12 weeks treatment with zofenopril 30 mg or candesartan 8 mg od. After 4 weeks, treatment was doubled in responder non-normalized (office systolic BP≥140 mmHg and office diastolic BP reduction ≥10 mmHg) or non-responder patients (office systolic BP≥140 mmHg and office diastolic BP reduction
Original language | English |
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Pages (from-to) | 18-26 |
Number of pages | 9 |
Journal | Blood Pressure |
Volume | 15 |
Issue number | SUPPL. 1 |
DOIs | |
Publication status | Published - Mar 2006 |
Keywords
- Ambulatory blood pressure monitoring
- Candesartan
- Primary hypertension
- Smoothness index
- Trough-to-peak ratio
- Zofenopril
ASJC Scopus subject areas
- Internal Medicine
- Cardiology and Cardiovascular Medicine