A Simple Method For Determination Of N-Nitrosamine Traces In Trifluralin Samples By Gas Chromatography-Mass Spectrometry

Rita Frassanito, Emilio Benfenati, Roberto Fanell, Giorgio Ciotti

Research output: Contribution to journalArticle

Abstract

A method for rapid quantitative determination of N-nitros amines (TV-dimethylnitrosamine NDMA, N-diethylnitrosamine NDEA, N-dipropylnitrosamine NDPA, N-dibutylnitrosamine NDBA) in pesticide samples was set up using the gas chromatographic-mass spectrometric (GC-MS) technique in the electron impact {El) mode. SIR, with deuterium labelled NDPA as a standard, was used for detection and quantification. Calculations were made on the basis of calibration curves, obtained by injecting different amounts of nitrosamines against a fixed concentration of deuterated NDPA, with a good linearity. We analysed several batches of trifluralin samples [2,6-dinitro-N, N-dipropyl-4-(trifluoromethyl) benzenamine], before and after purification steps. The sensitivity achieved by this method is lower than 2 ppb. This method can be easily used to detect /V-nitrosamine impurities in other pesticides, such as amides, carbamates, organophosphates, triazines, urea derivatives, other dinitroaniline-type and miscellaneous nitrogen-containing compounds.

Original languageEnglish
Pages (from-to)199-204
Number of pages6
JournalToxicological and Environmental Chemistry
Volume45
Issue number3-4
DOIs
Publication statusPublished - 1994

Keywords

  • chemical analysis
  • dinitroaniline-type pesticides
  • gas cromatography-mass spectrometry
  • pesticides
  • trifluralin
  • V-nitmsamines

ASJC Scopus subject areas

  • Environmental Chemistry
  • Health, Toxicology and Mutagenesis
  • Pollution
  • Environmental Science(all)
  • Toxicology

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