TY - JOUR
T1 - A simplified method to integrate metabolic images in stereotactic procedures using a PET/CT scanner
AU - Picozzi, Piero
AU - Rizzo, Giovanna
AU - Landoni, Claudio
AU - Attuati, Luca
AU - Franzin, Alberto
AU - Messa, Cristina
AU - Da Passano, Camillo Ferrari
AU - Bettinardi, Valentine
AU - Fazio, Ferruccio
PY - 2006/4
Y1 - 2006/4
N2 - We have developed a method that needs only the computed tomography (CT) indicator box to coregister positron emission tomography (PET) images and integrates this information with magnetic resonance imaging. The study was performed using a PET/CT scanner. A standard CT bed adapter was attached to the scanner couch. Then, the patient, with the Leksell G frame fixed, was positioned into the scanner with the CT indicator box. PET images were acquired using either [
18F]fluorodeoxyglucose or [
11C]choline as radioisotopes. After acquisition, CT and PET images were exported in DICOM 3 standard and transferred to a dedicated workstation via data link. Homemade software was implemented for multimodal image fusion. PET images were overwritten to their corresponding CT point values using a threshold algorithm, maintaining the stereotactic CT markers. The use of a CT indicator simplifies the procedure, because there is no need for a radioactive solution filling the indicator box. This method was tested first using a phantom and then in patients. The localization accuracy of the PET images is limited only by the slice thickness.
AB - We have developed a method that needs only the computed tomography (CT) indicator box to coregister positron emission tomography (PET) images and integrates this information with magnetic resonance imaging. The study was performed using a PET/CT scanner. A standard CT bed adapter was attached to the scanner couch. Then, the patient, with the Leksell G frame fixed, was positioned into the scanner with the CT indicator box. PET images were acquired using either [
18F]fluorodeoxyglucose or [
11C]choline as radioisotopes. After acquisition, CT and PET images were exported in DICOM 3 standard and transferred to a dedicated workstation via data link. Homemade software was implemented for multimodal image fusion. PET images were overwritten to their corresponding CT point values using a threshold algorithm, maintaining the stereotactic CT markers. The use of a CT indicator simplifies the procedure, because there is no need for a radioactive solution filling the indicator box. This method was tested first using a phantom and then in patients. The localization accuracy of the PET images is limited only by the slice thickness.
KW - Computed tomography/positron emission tomography
KW - Gamma Knife radiosurgery
KW - GammaPlan software
KW - Multimodal image processing
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U2 - 10.1159/000091951
DO - 10.1159/000091951
M3 - Article
C2 - 16534252
AN - SCOPUS:33645657608
VL - 83
SP - 208
EP - 212
JO - Stereotactic and Functional Neurosurgery
JF - Stereotactic and Functional Neurosurgery
SN - 1011-6125
IS - 5-6
ER -