A simplified method to integrate metabolic images in stereotactic procedures using a PET/CT scanner

Piero Picozzi, Giovanna Rizzo, Claudio Landoni, Luca Attuati, Alberto Franzin, Cristina Messa, Camillo Ferrari Da Passano, Valentine Bettinardi, Ferruccio Fazio

Research output: Contribution to journalArticlepeer-review


We have developed a method that needs only the computed tomography (CT) indicator box to coregister positron emission tomography (PET) images and integrates this information with magnetic resonance imaging. The study was performed using a PET/CT scanner. A standard CT bed adapter was attached to the scanner couch. Then, the patient, with the Leksell G frame fixed, was positioned into the scanner with the CT indicator box. PET images were acquired using either [ 18F]fluorodeoxyglucose or [ 11C]choline as radioisotopes. After acquisition, CT and PET images were exported in DICOM 3 standard and transferred to a dedicated workstation via data link. Homemade software was implemented for multimodal image fusion. PET images were overwritten to their corresponding CT point values using a threshold algorithm, maintaining the stereotactic CT markers. The use of a CT indicator simplifies the procedure, because there is no need for a radioactive solution filling the indicator box. This method was tested first using a phantom and then in patients. The localization accuracy of the PET images is limited only by the slice thickness.

Original languageEnglish
Pages (from-to)208-212
Number of pages5
JournalStereotactic and Functional Neurosurgery
Issue number5-6
Publication statusPublished - Apr 2006


  • Computed tomography/positron emission tomography
  • Gamma Knife radiosurgery
  • GammaPlan software
  • Multimodal image processing

ASJC Scopus subject areas

  • Clinical Neurology


Dive into the research topics of 'A simplified method to integrate metabolic images in stereotactic procedures using a PET/CT scanner'. Together they form a unique fingerprint.

Cite this