A single blind comparison of dihydroergotoxine mesilate and clonidine for treatment of hypertensive emergencies

E. Guffanti; A. Vaccarella; M. Meregalli; G. Fiorella; S. M. Chierichetti; C. Mazzola

A single blind comparison of dihydroergotoxine mesilate and clonidine for treatment of hypertensive emergencies

E. Guffanti, A. Vaccarella, M. Meregalli, G. Fiorella, S. M. Chierichetti, C. Mazzola

Istituto Nazionale di Riposo e Cura per Anziani V.E. II

Research output: Contribution to journal › Article › peer-review

Abstract

The effectiveness and safety of dihydroergotoxine mesylate (DHT) and clonidine (CLO) as acute antihypertensive treatments were studied in a single-blind randomized controlled study of 28 patients hospitalized after abrupt increases in mean blood pressure (MAP) to more than 150 mmHg, with concomitant symptoms related to hypertensive status (16 patients). Intravenous infusion of 1.5 mg DHT significantly reduced both systolic (SBP) and diastolic (DBP) blood pressure from 227 ± 2/128 ± 2 mmHg to 160 ± 4/94 ± 2 mmHg by 1 hour after the onset of infusion (p

Original language	English
Pages (from-to)	506-509
Number of pages	4
Journal	International Journal of Clinical Pharmacology Therapy and Toxicology
Volume	23
Issue number	9
Publication status	Published - 1985

ASJC Scopus subject areas

Toxicology
Pharmacology (medical)

Cite this

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year = "1985",

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AU - Guffanti, E.

AU - Vaccarella, A.

AU - Meregalli, M.

AU - Fiorella, G.

AU - Chierichetti, S. M.

AU - Mazzola, C.

PY - 1985

Y1 - 1985

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AB - The effectiveness and safety of dihydroergotoxine mesylate (DHT) and clonidine (CLO) as acute antihypertensive treatments were studied in a single-blind randomized controlled study of 28 patients hospitalized after abrupt increases in mean blood pressure (MAP) to more than 150 mmHg, with concomitant symptoms related to hypertensive status (16 patients). Intravenous infusion of 1.5 mg DHT significantly reduced both systolic (SBP) and diastolic (DBP) blood pressure from 227 ± 2/128 ± 2 mmHg to 160 ± 4/94 ± 2 mmHg by 1 hour after the onset of infusion (p

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A single blind comparison of dihydroergotoxine mesilate and clonidine for treatment of hypertensive emergencies

Abstract

ASJC Scopus subject areas

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