Abstract
The effectiveness and safety of dihydroergotoxine mesylate (DHT) and clonidine (CLO) as acute antihypertensive treatments were studied in a single-blind randomized controlled study of 28 patients hospitalized after abrupt increases in mean blood pressure (MAP) to more than 150 mmHg, with concomitant symptoms related to hypertensive status (16 patients). Intravenous infusion of 1.5 mg DHT significantly reduced both systolic (SBP) and diastolic (DBP) blood pressure from 227 ± 2/128 ± 2 mmHg to 160 ± 4/94 ± 2 mmHg by 1 hour after the onset of infusion (p
Original language | English |
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Pages (from-to) | 506-509 |
Number of pages | 4 |
Journal | International Journal of Clinical Pharmacology Therapy and Toxicology |
Volume | 23 |
Issue number | 9 |
Publication status | Published - 1985 |
ASJC Scopus subject areas
- Toxicology
- Pharmacology (medical)