A single-centre prospective, cohort study of the natural history of acute pancreatitis

Giulia Martina Cavestro, Gioacchino Leandro, Milena Di Leo, Raffaella Alessia Zuppardo, Olivia B. Morrow, Chiara Notaristefano, Gemma Rossi, Sabrina Gloria Giulia Testoni, Giorgia Mazzoleni, Matteo Alessandri, Elisabetta Goni, Satish K. Singh, Aurore Giliberti, Margherita Bianco, Lorella Fanti, Edi Viale, Paolo Giorgio Arcidiacono, Alberto Mariani, Maria Chiara Petrone, Pier Alberto Testoni

Research output: Contribution to journalArticle

Abstract

Background: The natural history of acute pancreatitis is based on clinical studies that aim to elucidate the course of disease on the basis of predicted risk factors. Aims: To evaluate the long-term occurrence of recurrent acute pancreatitis and chronic pancreatitis in a cohort of patients following an initial episode of acute pancreatitis. Methods: 196 patients were enrolled consecutively and studied prospectively. Clinical characteristics, exogenously/endogenously-associated factors, and evolution to recurrent acute pancreatitis and chronic pancreatitis were analyzed. Results: 40 patients developed recurrent acute pancreatitis 13 of whom developed chronic pancreatitis. In a univariate analysis, recurrent acute pancreatitis was associated with an idiopathic aetiology (p

Original languageEnglish
Pages (from-to)205-210
Number of pages6
JournalDigestive and Liver Disease
Volume47
Issue number3
DOIs
Publication statusPublished - Mar 1 2015

Keywords

  • Acute pancreatitis
  • Alcohol and smoking habits
  • Chronic pancreatitis
  • Pancreas divisum
  • Recurrent acute pancreatitis
  • Severe acute disease

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology
  • Medicine(all)

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  • Cite this

    Cavestro, G. M., Leandro, G., Di Leo, M., Zuppardo, R. A., Morrow, O. B., Notaristefano, C., Rossi, G., Testoni, S. G. G., Mazzoleni, G., Alessandri, M., Goni, E., Singh, S. K., Giliberti, A., Bianco, M., Fanti, L., Viale, E., Arcidiacono, P. G., Mariani, A., Petrone, M. C., & Testoni, P. A. (2015). A single-centre prospective, cohort study of the natural history of acute pancreatitis. Digestive and Liver Disease, 47(3), 205-210. https://doi.org/10.1016/j.dld.2014.11.003