A single nucleotide polymorphism in SLC1A1 gene is associated with age of onset of obsessive-compulsive disorder

S. Dallaspezia, M. Mazza, C. Lorenzi, F. Benedetti, E. Smeraldi

Research output: Contribution to journalArticle

Abstract

Different genetic polymorphisms in the SLC1A1 have been shown to be associated with obsessive-compulsive disorder. Rs301430 is a T/C functional polymorphism affecting the gene expression and extrasynaptic glutamate concentration.We observed that Rs301430 influence age at onset in obsessive-compulsive disorder.

Original languageEnglish
Pages (from-to)301-303
Number of pages3
JournalEuropean Psychiatry
Volume29
Issue number5
DOIs
Publication statusPublished - 2014

Fingerprint

Obsessive-Compulsive Disorder
Age of Onset
Single Nucleotide Polymorphism
Genetic Polymorphisms
Genes
Glutamic Acid
Gene Expression

Keywords

  • Age at onset
  • Glutamate
  • Obsessive-compulsive disorder
  • Rs301430
  • SLC1A1

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Medicine(all)

Cite this

A single nucleotide polymorphism in SLC1A1 gene is associated with age of onset of obsessive-compulsive disorder. / Dallaspezia, S.; Mazza, M.; Lorenzi, C.; Benedetti, F.; Smeraldi, E.

In: European Psychiatry, Vol. 29, No. 5, 2014, p. 301-303.

Research output: Contribution to journalArticle

@article{33cfda4a80ea4158bbb8f018c66f89b4,
title = "A single nucleotide polymorphism in SLC1A1 gene is associated with age of onset of obsessive-compulsive disorder",
abstract = "Different genetic polymorphisms in the SLC1A1 have been shown to be associated with obsessive-compulsive disorder. Rs301430 is a T/C functional polymorphism affecting the gene expression and extrasynaptic glutamate concentration.We observed that Rs301430 influence age at onset in obsessive-compulsive disorder.",
keywords = "Age at onset, Glutamate, Obsessive-compulsive disorder, Rs301430, SLC1A1",
author = "S. Dallaspezia and M. Mazza and C. Lorenzi and F. Benedetti and E. Smeraldi",
year = "2014",
doi = "10.1016/j.eurpsy.2014.02.006",
language = "English",
volume = "29",
pages = "301--303",
journal = "Psychiatrie et Psychobiologie",
issn = "0924-9338",
publisher = "Psychiatrie & psychobiologie",
number = "5",

}

TY - JOUR

T1 - A single nucleotide polymorphism in SLC1A1 gene is associated with age of onset of obsessive-compulsive disorder

AU - Dallaspezia, S.

AU - Mazza, M.

AU - Lorenzi, C.

AU - Benedetti, F.

AU - Smeraldi, E.

PY - 2014

Y1 - 2014

N2 - Different genetic polymorphisms in the SLC1A1 have been shown to be associated with obsessive-compulsive disorder. Rs301430 is a T/C functional polymorphism affecting the gene expression and extrasynaptic glutamate concentration.We observed that Rs301430 influence age at onset in obsessive-compulsive disorder.

AB - Different genetic polymorphisms in the SLC1A1 have been shown to be associated with obsessive-compulsive disorder. Rs301430 is a T/C functional polymorphism affecting the gene expression and extrasynaptic glutamate concentration.We observed that Rs301430 influence age at onset in obsessive-compulsive disorder.

KW - Age at onset

KW - Glutamate

KW - Obsessive-compulsive disorder

KW - Rs301430

KW - SLC1A1

UR - http://www.scopus.com/inward/record.url?scp=84902359057&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902359057&partnerID=8YFLogxK

U2 - 10.1016/j.eurpsy.2014.02.006

DO - 10.1016/j.eurpsy.2014.02.006

M3 - Article

C2 - 24768158

AN - SCOPUS:84902359057

VL - 29

SP - 301

EP - 303

JO - Psychiatrie et Psychobiologie

JF - Psychiatrie et Psychobiologie

SN - 0924-9338

IS - 5

ER -