A staging system for renal outcome and early markers of renal response to chemotherapy in AL amyloidosis

Giovanni Palladini; Ute Hegenbart; Paolo Milani; Christoph Kimmich; Andrea Foli; Anthony D. Ho; Marta Vidus Rosin; Riccardo Albertini; Remigio Moratti; Giampaolo Merlini; Stefan Schönland

doi:10.1182/blood-2014-04-570010

A staging system for renal outcome and early markers of renal response to chemotherapy in AL amyloidosis

Giovanni Palladini, Ute Hegenbart, Paolo Milani, Christoph Kimmich, Andrea Foli, Anthony D. Ho, Marta Vidus Rosin, Riccardo Albertini, Remigio Moratti, Giampaolo Merlini, Stefan Schönland

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

The kidney is involved in 70% of patients with immunoglobulin light-chain (AL) amyloidosis, but little is known on progression or reversibility of renal involvement, and criteria for renal response have never been validated. Newly diagnosed patients from the Pavia (n = 461, testing cohort) and Heidelberg (n = 271, validation cohort) centers were included. Proteinuria >5 g/24h and estimated glomerular filtration rate (eGFR)

Original language	English
Pages (from-to)	2325-2332
Number of pages	8
Journal	Blood
Volume	124
Issue number	15
DOIs	https://doi.org/10.1182/blood-2014-04-570010
Publication status	Published - Oct 9 2014

ASJC Scopus subject areas

Hematology
Biochemistry
Cell Biology
Immunology
Medicine(all)

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10.1182/blood-2014-04-570010

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A staging system for renal outcome and early markers of renal response to chemotherapy in AL amyloidosis. / Palladini, Giovanni; Hegenbart, Ute; Milani, Paolo; Kimmich, Christoph; Foli, Andrea; Ho, Anthony D.; Rosin, Marta Vidus; Albertini, Riccardo; Moratti, Remigio; Merlini, Giampaolo; Schönland, Stefan.

In: Blood, Vol. 124, No. 15, 09.10.2014, p. 2325-2332.

Research output: Contribution to journal › Article › peer-review

Palladini, Giovanni ; Hegenbart, Ute ; Milani, Paolo ; Kimmich, Christoph ; Foli, Andrea ; Ho, Anthony D. ; Rosin, Marta Vidus ; Albertini, Riccardo ; Moratti, Remigio ; Merlini, Giampaolo ; Schönland, Stefan. / A staging system for renal outcome and early markers of renal response to chemotherapy in AL amyloidosis. In: Blood. 2014 ; Vol. 124, No. 15. pp. 2325-2332.

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