A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B

R. El Sharkawy; K. Thabet; P. Lampertico; S. Petta; A. Mangia; T. Berg; M. Metwally; A. Bayoumi; A. Boonstra; W.P. Brouwer; A. Smedile; M.L. Abate; A. Loglio; M.W. Douglas; A. Khan; R. Santoro; J. Fischer; D.J. Leeming; C. Liddle; J. George; M. Eslam

doi:10.1111/apt.14866

A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B

R. El Sharkawy, K. Thabet, P. Lampertico, S. Petta, A. Mangia, T. Berg, M. Metwally, A. Bayoumi, A. Boonstra, W.P. Brouwer, A. Smedile, M.L. Abate, A. Loglio, M.W. Douglas, A. Khan, R. Santoro, J. Fischer, D.J. Leeming, C. Liddle, J. GeorgeM. Eslam

Research output: Contribution to journal › Article

Original language	English
Pages (from-to)	564-573
Number of pages	10
Journal	Alimentary Pharmacology and Therapeutics
Volume	48
Issue number	5
DOIs	https://doi.org/10.1111/apt.14866
Publication status	Published - 2018

Keywords

gamma interferon
interleukin 12
interleukin 18
STAT4 protein, adult
Article
Caucasian
chronic hepatitis B
controlled study
cytokine production
cytokine release
female
gene frequency
genetic association
genetic susceptibility
genetic variation
genotype
human
human cell
human tissue
liver fibrosis
liver tissue
lymphocyte function
major clinical study
male
natural killer cell
peripheral blood mononuclear cell
priority journal
protein analysis
protein expression
protein phosphorylation

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10.1111/apt.14866

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050387574&doi=10.1111%2fapt.14866&partnerID=40&md5=420a7506e8dbda45a14f816f544785c9

Cite this

El Sharkawy, R., Thabet, K., Lampertico, P., Petta, S., Mangia, A., Berg, T., Metwally, M., Bayoumi, A., Boonstra, A., Brouwer, W. P., Smedile, A., Abate, M. L., Loglio, A., Douglas, M. W., Khan, A., Santoro, R., Fischer, J., Leeming, D. J., Liddle, C., ... Eslam, M. (2018). A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B. Alimentary Pharmacology and Therapeutics, 48(5), 564-573. https://doi.org/10.1111/apt.14866

A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B. / El Sharkawy, R.; Thabet, K.; Lampertico, P.; Petta, S.; Mangia, A.; Berg, T.; Metwally, M.; Bayoumi, A.; Boonstra, A.; Brouwer, W.P.; Smedile, A.; Abate, M.L.; Loglio, A.; Douglas, M.W.; Khan, A.; Santoro, R.; Fischer, J.; Leeming, D.J.; Liddle, C.; George, J.; Eslam, M.

In: Alimentary Pharmacology and Therapeutics, Vol. 48, No. 5, 2018, p. 564-573.

Research output: Contribution to journal › Article

El Sharkawy, R, Thabet, K, Lampertico, P, Petta, S, Mangia, A, Berg, T, Metwally, M, Bayoumi, A, Boonstra, A, Brouwer, WP, Smedile, A, Abate, ML, Loglio, A, Douglas, MW, Khan, A, Santoro, R, Fischer, J, Leeming, DJ, Liddle, C, George, J & Eslam, M 2018, 'A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B', Alimentary Pharmacology and Therapeutics, vol. 48, no. 5, pp. 564-573. https://doi.org/10.1111/apt.14866

El Sharkawy, R. ; Thabet, K. ; Lampertico, P. ; Petta, S. ; Mangia, A. ; Berg, T. ; Metwally, M. ; Bayoumi, A. ; Boonstra, A. ; Brouwer, W.P. ; Smedile, A. ; Abate, M.L. ; Loglio, A. ; Douglas, M.W. ; Khan, A. ; Santoro, R. ; Fischer, J. ; Leeming, D.J. ; Liddle, C. ; George, J. ; Eslam, M. / A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B. In: Alimentary Pharmacology and Therapeutics. 2018 ; Vol. 48, No. 5. pp. 564-573.

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keywords = "gamma interferon, interleukin 12, interleukin 18, STAT4 protein, adult, Article, Caucasian, chronic hepatitis B, controlled study, cytokine production, cytokine release, female, gene frequency, genetic association, genetic susceptibility, genetic variation, genotype, human, human cell, human tissue, liver fibrosis, liver tissue, lymphocyte function, major clinical study, male, natural killer cell, peripheral blood mononuclear cell, priority journal, protein analysis, protein expression, protein phosphorylation",

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AU - Mangia, A.

AU - Berg, T.

AU - Metwally, M.

AU - Bayoumi, A.

AU - Boonstra, A.

AU - Brouwer, W.P.

AU - Smedile, A.

AU - Abate, M.L.

AU - Loglio, A.

AU - Douglas, M.W.

AU - Khan, A.

AU - Santoro, R.

AU - Fischer, J.

AU - Leeming, D.J.

AU - Liddle, C.

AU - George, J.

AU - Eslam, M.

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