A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B

R. El Sharkawy, K. Thabet, P. Lampertico, S. Petta, A. Mangia, T. Berg, M. Metwally, A. Bayoumi, A. Boonstra, W.P. Brouwer, A. Smedile, M.L. Abate, A. Loglio, M.W. Douglas, A. Khan, R. Santoro, J. Fischer, D.J. Leeming, C. Liddle, J. GeorgeM. Eslam

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)564-573
Number of pages10
JournalAlimentary Pharmacology and Therapeutics
Volume48
Issue number5
DOIs
Publication statusPublished - 2018

Keywords

  • gamma interferon
  • interleukin 12
  • interleukin 18
  • STAT4 protein, adult
  • Article
  • Caucasian
  • chronic hepatitis B
  • controlled study
  • cytokine production
  • cytokine release
  • female
  • gene frequency
  • genetic association
  • genetic susceptibility
  • genetic variation
  • genotype
  • human
  • human cell
  • human tissue
  • liver fibrosis
  • liver tissue
  • lymphocyte function
  • major clinical study
  • male
  • natural killer cell
  • peripheral blood mononuclear cell
  • priority journal
  • protein analysis
  • protein expression
  • protein phosphorylation

Cite this

A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B. / El Sharkawy, R.; Thabet, K.; Lampertico, P.; Petta, S.; Mangia, A.; Berg, T.; Metwally, M.; Bayoumi, A.; Boonstra, A.; Brouwer, W.P.; Smedile, A.; Abate, M.L.; Loglio, A.; Douglas, M.W.; Khan, A.; Santoro, R.; Fischer, J.; Leeming, D.J.; Liddle, C.; George, J.; Eslam, M.

In: Alimentary Pharmacology and Therapeutics, Vol. 48, No. 5, 2018, p. 564-573.

Research output: Contribution to journalArticle

El Sharkawy, R, Thabet, K, Lampertico, P, Petta, S, Mangia, A, Berg, T, Metwally, M, Bayoumi, A, Boonstra, A, Brouwer, WP, Smedile, A, Abate, ML, Loglio, A, Douglas, MW, Khan, A, Santoro, R, Fischer, J, Leeming, DJ, Liddle, C, George, J & Eslam, M 2018, 'A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B', Alimentary Pharmacology and Therapeutics, vol. 48, no. 5, pp. 564-573. https://doi.org/10.1111/apt.14866
El Sharkawy, R. ; Thabet, K. ; Lampertico, P. ; Petta, S. ; Mangia, A. ; Berg, T. ; Metwally, M. ; Bayoumi, A. ; Boonstra, A. ; Brouwer, W.P. ; Smedile, A. ; Abate, M.L. ; Loglio, A. ; Douglas, M.W. ; Khan, A. ; Santoro, R. ; Fischer, J. ; Leeming, D.J. ; Liddle, C. ; George, J. ; Eslam, M. / A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B. In: Alimentary Pharmacology and Therapeutics. 2018 ; Vol. 48, No. 5. pp. 564-573.
@article{ae3346c02e6e487594f650f6b23bd3a8,
title = "A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B",
keywords = "gamma interferon, interleukin 12, interleukin 18, STAT4 protein, adult, Article, Caucasian, chronic hepatitis B, controlled study, cytokine production, cytokine release, female, gene frequency, genetic association, genetic susceptibility, genetic variation, genotype, human, human cell, human tissue, liver fibrosis, liver tissue, lymphocyte function, major clinical study, male, natural killer cell, peripheral blood mononuclear cell, priority journal, protein analysis, protein expression, protein phosphorylation",
author = "{El Sharkawy}, R. and K. Thabet and P. Lampertico and S. Petta and A. Mangia and T. Berg and M. Metwally and A. Bayoumi and A. Boonstra and W.P. Brouwer and A. Smedile and M.L. Abate and A. Loglio and M.W. Douglas and A. Khan and R. Santoro and J. Fischer and D.J. Leeming and C. Liddle and J. George and M. Eslam",
note = "cited By 2",
year = "2018",
doi = "10.1111/apt.14866",
language = "English",
volume = "48",
pages = "564--573",
journal = "Alimentary Pharmacology and Therapeutics",
issn = "0269-2813",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "5",

}

TY - JOUR

T1 - A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B

AU - El Sharkawy, R.

AU - Thabet, K.

AU - Lampertico, P.

AU - Petta, S.

AU - Mangia, A.

AU - Berg, T.

AU - Metwally, M.

AU - Bayoumi, A.

AU - Boonstra, A.

AU - Brouwer, W.P.

AU - Smedile, A.

AU - Abate, M.L.

AU - Loglio, A.

AU - Douglas, M.W.

AU - Khan, A.

AU - Santoro, R.

AU - Fischer, J.

AU - Leeming, D.J.

AU - Liddle, C.

AU - George, J.

AU - Eslam, M.

N1 - cited By 2

PY - 2018

Y1 - 2018

KW - gamma interferon

KW - interleukin 12

KW - interleukin 18

KW - STAT4 protein, adult

KW - Article

KW - Caucasian

KW - chronic hepatitis B

KW - controlled study

KW - cytokine production

KW - cytokine release

KW - female

KW - gene frequency

KW - genetic association

KW - genetic susceptibility

KW - genetic variation

KW - genotype

KW - human

KW - human cell

KW - human tissue

KW - liver fibrosis

KW - liver tissue

KW - lymphocyte function

KW - major clinical study

KW - male

KW - natural killer cell

KW - peripheral blood mononuclear cell

KW - priority journal

KW - protein analysis

KW - protein expression

KW - protein phosphorylation

U2 - 10.1111/apt.14866

DO - 10.1111/apt.14866

M3 - Article

VL - 48

SP - 564

EP - 573

JO - Alimentary Pharmacology and Therapeutics

JF - Alimentary Pharmacology and Therapeutics

SN - 0269-2813

IS - 5

ER -