Abstract
Due to the fact that not all pigmented skin lesions (PSL) can be diagnosed solely by their clinical appearance, additional criteria are required to optimize the clinical diagnosis of atypical nevus and melanoma. Epiluminescence microscopy is a non-invasive in vivo examination that often helps to improved the accuracy of clinical diagnosis of such lesions. Years of experience have indicated some differential epiluminescent patterns for benign and malignant PSI, but there is some controversy about certain borderline lesions for which histological examination is always necessary. In our study we performed a statistical analysis of data concerning 183 PSI, to determine characteristics significantly associated with these lesions allowing identification of epiluminescent criteria suggestive of atypical nevus and malignant melanoma. Using he chi-quadro test and stepwise regression logistic model, we identified the following epiluminescent pattern as a risk factor for atypical nevus and malignant melanoma: irregular pigment network, presence of capillaries, irregular and abrupt ending of overall pigmentation, irregular brown globules and irregular shape and size of black dots.
| Original language | English |
|---|---|
| Pages (from-to) | 243-248 |
| Number of pages | 6 |
| Journal | Journal of the European Academy of Dermatology and Venereology |
| Volume | 9 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1997 |
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Keywords
- Epiluminescence microscopy
- Pigmented skin lesions
- Statistical analysis
ASJC Scopus subject areas
- Dermatology
- Infectious Diseases
Cite this
A statistical analysis of the characteristics of pigmented skin lesions using epiluminescence microscopy. / Delfino, M.; Fabbrocini, G.; Argenziano, G.; Magliocchetti, N.; Nofroni, I.
In: Journal of the European Academy of Dermatology and Venereology, Vol. 9, No. 3, 1997, p. 243-248.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A statistical analysis of the characteristics of pigmented skin lesions using epiluminescence microscopy
AU - Delfino, M.
AU - Fabbrocini, G.
AU - Argenziano, G.
AU - Magliocchetti, N.
AU - Nofroni, I.
PY - 1997
Y1 - 1997
N2 - Due to the fact that not all pigmented skin lesions (PSL) can be diagnosed solely by their clinical appearance, additional criteria are required to optimize the clinical diagnosis of atypical nevus and melanoma. Epiluminescence microscopy is a non-invasive in vivo examination that often helps to improved the accuracy of clinical diagnosis of such lesions. Years of experience have indicated some differential epiluminescent patterns for benign and malignant PSI, but there is some controversy about certain borderline lesions for which histological examination is always necessary. In our study we performed a statistical analysis of data concerning 183 PSI, to determine characteristics significantly associated with these lesions allowing identification of epiluminescent criteria suggestive of atypical nevus and malignant melanoma. Using he chi-quadro test and stepwise regression logistic model, we identified the following epiluminescent pattern as a risk factor for atypical nevus and malignant melanoma: irregular pigment network, presence of capillaries, irregular and abrupt ending of overall pigmentation, irregular brown globules and irregular shape and size of black dots.
AB - Due to the fact that not all pigmented skin lesions (PSL) can be diagnosed solely by their clinical appearance, additional criteria are required to optimize the clinical diagnosis of atypical nevus and melanoma. Epiluminescence microscopy is a non-invasive in vivo examination that often helps to improved the accuracy of clinical diagnosis of such lesions. Years of experience have indicated some differential epiluminescent patterns for benign and malignant PSI, but there is some controversy about certain borderline lesions for which histological examination is always necessary. In our study we performed a statistical analysis of data concerning 183 PSI, to determine characteristics significantly associated with these lesions allowing identification of epiluminescent criteria suggestive of atypical nevus and malignant melanoma. Using he chi-quadro test and stepwise regression logistic model, we identified the following epiluminescent pattern as a risk factor for atypical nevus and malignant melanoma: irregular pigment network, presence of capillaries, irregular and abrupt ending of overall pigmentation, irregular brown globules and irregular shape and size of black dots.
KW - Epiluminescence microscopy
KW - Pigmented skin lesions
KW - Statistical analysis
UR - http://www.scopus.com/inward/record.url?scp=0031458244&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031458244&partnerID=8YFLogxK
U2 - 10.1016/S0926-9959(97)00134-7
DO - 10.1016/S0926-9959(97)00134-7
M3 - Article
AN - SCOPUS:0031458244
VL - 9
SP - 243
EP - 248
JO - Journal of the European Academy of Dermatology and Venereology
JF - Journal of the European Academy of Dermatology and Venereology
SN - 0926-9959
IS - 3
ER -