A straightforward multiparametric quality control protocol for proton magnetic resonance spectroscopy: Validation and comparison of various 1.5 T and 3 T clinical scanner systems

Italian Association of Physics in Medicine (AIFM) Working Group on Quantification and Intercomparison in MR

Research output: Contribution to journalArticle

Abstract

PURPOSE: The aim of this study was to propose and validate across various clinical scanner systems a straightforward multiparametric quality assurance procedure for proton magnetic resonance spectroscopy (MRS).

METHODS: Eighteen clinical 1.5 T and 3 T scanner systems for MRS, from 16 centres and 3 different manufacturers, were enrolled in the study. A standard spherical water phantom was employed by all centres. The acquisition protocol included 3 sets of single (isotropic) voxel (size 20 mm) PRESS acquisitions with unsuppressed water signal and acquisition voxel position at isocenter as well as off-center, repeated 4/5 times within approximately 2 months. Water peak linewidth (LW) and area under the water peak (AP) were estimated.

RESULTS: LW values [mean (standard deviation)] were 1.4 (1.0) Hz and 0.8 (0.3) Hz for 3 T and 1.5 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficient of variation of LW and AP for different spatial positions of acquisition voxel were 43% (20%) and 11% (11%), respectively. The mean (standard deviation) phantom T2values were 1145 (50) ms and 1010 (95) ms for 1.5 T and 3 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficients of variation for repeated measurements of LW, AP and T2 were 25% (20%), 10% (14%) and 5% (2%), respectively.

CONCLUSIONS: We proposed a straightforward multiparametric and not time consuming quality control protocol for MRS, which can be included in routine and periodic quality assurance procedures. The protocol has been validated and proven to be feasible in a multicentre comparison study of a fairly large number of clinical 1.5 T and 3 T scanner systems.

Original languageEnglish
Pages (from-to)49-55
Number of pages7
JournalPhysica Medica
Volume54
DOIs
Publication statusPublished - Oct 2018

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proton magnetic resonance
magnetic resonance spectroscopy
quality control
Quality Control
scanners
Water
standard deviation
acquisition
Magnetic Resonance Spectroscopy
assurance
water
Multicenter Studies
coefficients
Proton Magnetic Resonance Spectroscopy

Keywords

  • Phantoms, Imaging
  • Proton Magnetic Resonance Spectroscopy/standards
  • Quality Control

Cite this

A straightforward multiparametric quality control protocol for proton magnetic resonance spectroscopy : Validation and comparison of various 1.5 T and 3 T clinical scanner systems. / Italian Association of Physics in Medicine (AIFM) Working Group on Quantification and Intercomparison in MR.

In: Physica Medica, Vol. 54, 10.2018, p. 49-55.

Research output: Contribution to journalArticle

Italian Association of Physics in Medicine (AIFM) Working Group on Quantification and Intercomparison in MR. / A straightforward multiparametric quality control protocol for proton magnetic resonance spectroscopy : Validation and comparison of various 1.5 T and 3 T clinical scanner systems. In: Physica Medica. 2018 ; Vol. 54. pp. 49-55.
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abstract = "PURPOSE: The aim of this study was to propose and validate across various clinical scanner systems a straightforward multiparametric quality assurance procedure for proton magnetic resonance spectroscopy (MRS).METHODS: Eighteen clinical 1.5 T and 3 T scanner systems for MRS, from 16 centres and 3 different manufacturers, were enrolled in the study. A standard spherical water phantom was employed by all centres. The acquisition protocol included 3 sets of single (isotropic) voxel (size 20 mm) PRESS acquisitions with unsuppressed water signal and acquisition voxel position at isocenter as well as off-center, repeated 4/5 times within approximately 2 months. Water peak linewidth (LW) and area under the water peak (AP) were estimated.RESULTS: LW values [mean (standard deviation)] were 1.4 (1.0) Hz and 0.8 (0.3) Hz for 3 T and 1.5 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficient of variation of LW and AP for different spatial positions of acquisition voxel were 43{\%} (20{\%}) and 11{\%} (11{\%}), respectively. The mean (standard deviation) phantom T2values were 1145 (50) ms and 1010 (95) ms for 1.5 T and 3 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficients of variation for repeated measurements of LW, AP and T2 were 25{\%} (20{\%}), 10{\%} (14{\%}) and 5{\%} (2{\%}), respectively.CONCLUSIONS: We proposed a straightforward multiparametric and not time consuming quality control protocol for MRS, which can be included in routine and periodic quality assurance procedures. The protocol has been validated and proven to be feasible in a multicentre comparison study of a fairly large number of clinical 1.5 T and 3 T scanner systems.",
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author = "{Italian Association of Physics in Medicine (AIFM) Working Group on Quantification and Intercomparison in MR} and Roberto Sghedoni and Angela Coniglio and Mazzoni, {Lorenzo Nicola} and Simone Busoni and Giacomo Belli and Roberto Tarducci and Luca Nocetti and Luca Fedeli and Marco Esposito and Antonio Ciccarone and Luisa Altabella and Alessandro Bellini and Luca Binotto and Rocchina Caivano and Marco Carn{\`i} and Alessandra Ricci and Sara Cimolai and Davide D'Urso and Chiara Gasperi and Fabrizio Levrero and Paola Mangili and Sabrina Morzenti and Andrea Nitrosi and Nadia Oberhofer and Nicoletta Parruccini and Alessandra Toncelli and Valastro, {Lucia Maria} and Cesare Gori and Gianni Gobbi and Marco Giannelli",
note = "Copyright {\circledC} 2018 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.",
year = "2018",
month = "10",
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language = "English",
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TY - JOUR

T1 - A straightforward multiparametric quality control protocol for proton magnetic resonance spectroscopy

T2 - Validation and comparison of various 1.5 T and 3 T clinical scanner systems

AU - Italian Association of Physics in Medicine (AIFM) Working Group on Quantification and Intercomparison in MR

AU - Sghedoni, Roberto

AU - Coniglio, Angela

AU - Mazzoni, Lorenzo Nicola

AU - Busoni, Simone

AU - Belli, Giacomo

AU - Tarducci, Roberto

AU - Nocetti, Luca

AU - Fedeli, Luca

AU - Esposito, Marco

AU - Ciccarone, Antonio

AU - Altabella, Luisa

AU - Bellini, Alessandro

AU - Binotto, Luca

AU - Caivano, Rocchina

AU - Carnì, Marco

AU - Ricci, Alessandra

AU - Cimolai, Sara

AU - D'Urso, Davide

AU - Gasperi, Chiara

AU - Levrero, Fabrizio

AU - Mangili, Paola

AU - Morzenti, Sabrina

AU - Nitrosi, Andrea

AU - Oberhofer, Nadia

AU - Parruccini, Nicoletta

AU - Toncelli, Alessandra

AU - Valastro, Lucia Maria

AU - Gori, Cesare

AU - Gobbi, Gianni

AU - Giannelli, Marco

N1 - Copyright © 2018 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

PY - 2018/10

Y1 - 2018/10

N2 - PURPOSE: The aim of this study was to propose and validate across various clinical scanner systems a straightforward multiparametric quality assurance procedure for proton magnetic resonance spectroscopy (MRS).METHODS: Eighteen clinical 1.5 T and 3 T scanner systems for MRS, from 16 centres and 3 different manufacturers, were enrolled in the study. A standard spherical water phantom was employed by all centres. The acquisition protocol included 3 sets of single (isotropic) voxel (size 20 mm) PRESS acquisitions with unsuppressed water signal and acquisition voxel position at isocenter as well as off-center, repeated 4/5 times within approximately 2 months. Water peak linewidth (LW) and area under the water peak (AP) were estimated.RESULTS: LW values [mean (standard deviation)] were 1.4 (1.0) Hz and 0.8 (0.3) Hz for 3 T and 1.5 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficient of variation of LW and AP for different spatial positions of acquisition voxel were 43% (20%) and 11% (11%), respectively. The mean (standard deviation) phantom T2values were 1145 (50) ms and 1010 (95) ms for 1.5 T and 3 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficients of variation for repeated measurements of LW, AP and T2 were 25% (20%), 10% (14%) and 5% (2%), respectively.CONCLUSIONS: We proposed a straightforward multiparametric and not time consuming quality control protocol for MRS, which can be included in routine and periodic quality assurance procedures. The protocol has been validated and proven to be feasible in a multicentre comparison study of a fairly large number of clinical 1.5 T and 3 T scanner systems.

AB - PURPOSE: The aim of this study was to propose and validate across various clinical scanner systems a straightforward multiparametric quality assurance procedure for proton magnetic resonance spectroscopy (MRS).METHODS: Eighteen clinical 1.5 T and 3 T scanner systems for MRS, from 16 centres and 3 different manufacturers, were enrolled in the study. A standard spherical water phantom was employed by all centres. The acquisition protocol included 3 sets of single (isotropic) voxel (size 20 mm) PRESS acquisitions with unsuppressed water signal and acquisition voxel position at isocenter as well as off-center, repeated 4/5 times within approximately 2 months. Water peak linewidth (LW) and area under the water peak (AP) were estimated.RESULTS: LW values [mean (standard deviation)] were 1.4 (1.0) Hz and 0.8 (0.3) Hz for 3 T and 1.5 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficient of variation of LW and AP for different spatial positions of acquisition voxel were 43% (20%) and 11% (11%), respectively. The mean (standard deviation) phantom T2values were 1145 (50) ms and 1010 (95) ms for 1.5 T and 3 T scanners, respectively. The mean (standard deviation) (across all scanners) coefficients of variation for repeated measurements of LW, AP and T2 were 25% (20%), 10% (14%) and 5% (2%), respectively.CONCLUSIONS: We proposed a straightforward multiparametric and not time consuming quality control protocol for MRS, which can be included in routine and periodic quality assurance procedures. The protocol has been validated and proven to be feasible in a multicentre comparison study of a fairly large number of clinical 1.5 T and 3 T scanner systems.

KW - Phantoms, Imaging

KW - Proton Magnetic Resonance Spectroscopy/standards

KW - Quality Control

U2 - 10.1016/j.ejmp.2018.08.013

DO - 10.1016/j.ejmp.2018.08.013

M3 - Article

C2 - 30337010

VL - 54

SP - 49

EP - 55

JO - Physica Medica

JF - Physica Medica

SN - 1120-1797

ER -