Abstract
A study was carried out in 15 male volunteers to evaluate qualitatively the secretion of growth factors following stimulation by oral amino acids. The results showed that oral administration of a combination of two amino acids (1200 mg l-lysine plus 1200 mg l-arginine) provoked a release of pituitary somatotropin and insulin. This phenomenon was reproducible and the growth hormone secreted in response to this stimulation had biological activity {as demonstrated by a radioreceptor assay and somatomedin induction). The effect appeared to be specific to the combination of the two amino acids; neither of the amino acids demonstrated appreciable stimulating activity when administered alone, even at the same doses.
Original language | English |
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Pages (from-to) | 475-481 |
Number of pages | 7 |
Journal | Current Medical Research and Opinion |
Volume | 7 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1981 |
Keywords
- Arginine
- Drug Combinations
- Growth Hormone
- Lysine
ASJC Scopus subject areas
- Medicine(all)