A study of repeated measures of hemodynamics, muscle sympathetic nerve activity and their spectral oscillations

V. K. Somers, P. Van De Borne, N. Montano, M. Pagani, B. Zimmerman

Research output: Contribution to journalArticle

Abstract

Background: Low-frequency (LF) and high-frequency (HF) components of RR interval (RR) variability are widely used as indirect markers of cardiac autonomic control but their reproducibility is unknown. We determined the intra-class correlation coefficients (ICC) of repeated measures of the mean levels and variability of RR and muscle sympathetic nerve activity (MSNA) in 7 normal subjects. We also determined whether spontaneous fluctuations in RR and MSNA over repeated measurements were mirrored by fluctuations in spectral components of these variables. Methods: Twenty minute recordings of respiration, RR, blood pressure (BP) and MSNA were performed at day 1, 1 week, 1 month and 3 months. Comparison between these recordings determined the long-term reliability. Results: The long-term reliability of the variability of RR was comparable to the variability of MSNA (range of ICC: .34 - .52). Spontaneous decreases in RR during the repeated recordings were paralleled by increases in the ratio of low-frequency to high-frequency variability (LF:HF ratio) of RR interval (r=-.43, p

Original languageEnglish
JournalFASEB Journal
Volume11
Issue number3
Publication statusPublished - 1997

Fingerprint

Hemodynamics
hemodynamics
Muscle
oscillation
nerve tissue
Muscles
muscles
Blood pressure
Respiration
Blood Pressure
reproducibility
breathing
blood pressure

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

Cite this

A study of repeated measures of hemodynamics, muscle sympathetic nerve activity and their spectral oscillations. / Somers, V. K.; Van De Borne, P.; Montano, N.; Pagani, M.; Zimmerman, B.

In: FASEB Journal, Vol. 11, No. 3, 1997.

Research output: Contribution to journalArticle

Somers, V. K. ; Van De Borne, P. ; Montano, N. ; Pagani, M. ; Zimmerman, B. / A study of repeated measures of hemodynamics, muscle sympathetic nerve activity and their spectral oscillations. In: FASEB Journal. 1997 ; Vol. 11, No. 3.
@article{b0dc957559474aff875e24735b5b80ef,
title = "A study of repeated measures of hemodynamics, muscle sympathetic nerve activity and their spectral oscillations",
abstract = "Background: Low-frequency (LF) and high-frequency (HF) components of RR interval (RR) variability are widely used as indirect markers of cardiac autonomic control but their reproducibility is unknown. We determined the intra-class correlation coefficients (ICC) of repeated measures of the mean levels and variability of RR and muscle sympathetic nerve activity (MSNA) in 7 normal subjects. We also determined whether spontaneous fluctuations in RR and MSNA over repeated measurements were mirrored by fluctuations in spectral components of these variables. Methods: Twenty minute recordings of respiration, RR, blood pressure (BP) and MSNA were performed at day 1, 1 week, 1 month and 3 months. Comparison between these recordings determined the long-term reliability. Results: The long-term reliability of the variability of RR was comparable to the variability of MSNA (range of ICC: .34 - .52). Spontaneous decreases in RR during the repeated recordings were paralleled by increases in the ratio of low-frequency to high-frequency variability (LF:HF ratio) of RR interval (r=-.43, p",
author = "Somers, {V. K.} and {Van De Borne}, P. and N. Montano and M. Pagani and B. Zimmerman",
year = "1997",
language = "English",
volume = "11",
journal = "FASEB Journal",
issn = "0892-6638",
publisher = "FASEB",
number = "3",

}

TY - JOUR

T1 - A study of repeated measures of hemodynamics, muscle sympathetic nerve activity and their spectral oscillations

AU - Somers, V. K.

AU - Van De Borne, P.

AU - Montano, N.

AU - Pagani, M.

AU - Zimmerman, B.

PY - 1997

Y1 - 1997

N2 - Background: Low-frequency (LF) and high-frequency (HF) components of RR interval (RR) variability are widely used as indirect markers of cardiac autonomic control but their reproducibility is unknown. We determined the intra-class correlation coefficients (ICC) of repeated measures of the mean levels and variability of RR and muscle sympathetic nerve activity (MSNA) in 7 normal subjects. We also determined whether spontaneous fluctuations in RR and MSNA over repeated measurements were mirrored by fluctuations in spectral components of these variables. Methods: Twenty minute recordings of respiration, RR, blood pressure (BP) and MSNA were performed at day 1, 1 week, 1 month and 3 months. Comparison between these recordings determined the long-term reliability. Results: The long-term reliability of the variability of RR was comparable to the variability of MSNA (range of ICC: .34 - .52). Spontaneous decreases in RR during the repeated recordings were paralleled by increases in the ratio of low-frequency to high-frequency variability (LF:HF ratio) of RR interval (r=-.43, p

AB - Background: Low-frequency (LF) and high-frequency (HF) components of RR interval (RR) variability are widely used as indirect markers of cardiac autonomic control but their reproducibility is unknown. We determined the intra-class correlation coefficients (ICC) of repeated measures of the mean levels and variability of RR and muscle sympathetic nerve activity (MSNA) in 7 normal subjects. We also determined whether spontaneous fluctuations in RR and MSNA over repeated measurements were mirrored by fluctuations in spectral components of these variables. Methods: Twenty minute recordings of respiration, RR, blood pressure (BP) and MSNA were performed at day 1, 1 week, 1 month and 3 months. Comparison between these recordings determined the long-term reliability. Results: The long-term reliability of the variability of RR was comparable to the variability of MSNA (range of ICC: .34 - .52). Spontaneous decreases in RR during the repeated recordings were paralleled by increases in the ratio of low-frequency to high-frequency variability (LF:HF ratio) of RR interval (r=-.43, p

UR - http://www.scopus.com/inward/record.url?scp=33750261455&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750261455&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33750261455

VL - 11

JO - FASEB Journal

JF - FASEB Journal

SN - 0892-6638

IS - 3

ER -