Abstract
Background: Low-frequency (LF) and high-frequency (HF) components of RR interval (RR) variability are widely used as indirect markers of cardiac autonomic control but their reproducibility is unknown. We determined the intra-class correlation coefficients (ICC) of repeated measures of the mean levels and variability of RR and muscle sympathetic nerve activity (MSNA) in 7 normal subjects. We also determined whether spontaneous fluctuations in RR and MSNA over repeated measurements were mirrored by fluctuations in spectral components of these variables. Methods: Twenty minute recordings of respiration, RR, blood pressure (BP) and MSNA were performed at day 1, 1 week, 1 month and 3 months. Comparison between these recordings determined the long-term reliability. Results: The long-term reliability of the variability of RR was comparable to the variability of MSNA (range of ICC: .34 - .52). Spontaneous decreases in RR during the repeated recordings were paralleled by increases in the ratio of low-frequency to high-frequency variability (LF:HF ratio) of RR interval (r=-.43, p
| Original language | English |
|---|---|
| Journal | FASEB Journal |
| Volume | 11 |
| Issue number | 3 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Agricultural and Biological Sciences (miscellaneous)
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Cell Biology
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A study of repeated measures of hemodynamics, muscle sympathetic nerve activity and their spectral oscillations. / Somers, V. K.; Van De Borne, P.; Montano, N.; Pagani, M.; Zimmerman, B.
In: FASEB Journal, Vol. 11, No. 3, 1997.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A study of repeated measures of hemodynamics, muscle sympathetic nerve activity and their spectral oscillations
AU - Somers, V. K.
AU - Van De Borne, P.
AU - Montano, N.
AU - Pagani, M.
AU - Zimmerman, B.
PY - 1997
Y1 - 1997
N2 - Background: Low-frequency (LF) and high-frequency (HF) components of RR interval (RR) variability are widely used as indirect markers of cardiac autonomic control but their reproducibility is unknown. We determined the intra-class correlation coefficients (ICC) of repeated measures of the mean levels and variability of RR and muscle sympathetic nerve activity (MSNA) in 7 normal subjects. We also determined whether spontaneous fluctuations in RR and MSNA over repeated measurements were mirrored by fluctuations in spectral components of these variables. Methods: Twenty minute recordings of respiration, RR, blood pressure (BP) and MSNA were performed at day 1, 1 week, 1 month and 3 months. Comparison between these recordings determined the long-term reliability. Results: The long-term reliability of the variability of RR was comparable to the variability of MSNA (range of ICC: .34 - .52). Spontaneous decreases in RR during the repeated recordings were paralleled by increases in the ratio of low-frequency to high-frequency variability (LF:HF ratio) of RR interval (r=-.43, p
AB - Background: Low-frequency (LF) and high-frequency (HF) components of RR interval (RR) variability are widely used as indirect markers of cardiac autonomic control but their reproducibility is unknown. We determined the intra-class correlation coefficients (ICC) of repeated measures of the mean levels and variability of RR and muscle sympathetic nerve activity (MSNA) in 7 normal subjects. We also determined whether spontaneous fluctuations in RR and MSNA over repeated measurements were mirrored by fluctuations in spectral components of these variables. Methods: Twenty minute recordings of respiration, RR, blood pressure (BP) and MSNA were performed at day 1, 1 week, 1 month and 3 months. Comparison between these recordings determined the long-term reliability. Results: The long-term reliability of the variability of RR was comparable to the variability of MSNA (range of ICC: .34 - .52). Spontaneous decreases in RR during the repeated recordings were paralleled by increases in the ratio of low-frequency to high-frequency variability (LF:HF ratio) of RR interval (r=-.43, p
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UR - http://www.scopus.com/inward/citedby.url?scp=33750261455&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:33750261455
VL - 11
JO - FASEB Journal
JF - FASEB Journal
SN - 0892-6638
IS - 3
ER -