A successful dietary treatment fails to normalize plasma triglyceride postprandial response in type IV patients

Adele Zoppo, Franco M. Maggi, Alberico L. Catapano

Research output: Contribution to journalArticlepeer-review

Abstract

The role of plasma triglycerides as a risk factor for cardiovascular disease is still under scrutiny. While recent studies have shown that postprandial triglyceridemia is an independent risk factor, normalization of fasting plasma triglycerides through modification of nutritional habits remains the primary approach in the treatment of hypertriglyceridemia. To address the issue of whether a satisfactory dietary regimen results in the control of postprandial lipemia, 53 type IV hypertriglyceridemic patients underwent an hypolipidemic diet for 3 months. All patients had a reduction of fasting lipid parameters (average TG: from 516±208 to 229±99 mg/dl; total cholesterol (Chol): from 261±42 to 213±40 mg/dl and HDL Chol: from 33±9 to 38±8 mg/dl). Taking plasma TG≤200 mg/dl as the target for dietary intervention 26 patients were classified as 'responders' while the remaining 27 were 'non responders'. Even if fasting total TG, total Chol, HDL and LDL Chol were normal, both responders and non responders (P

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalAtherosclerosis
Volume146
Issue number1
DOIs
Publication statusPublished - Sep 1999

Keywords

  • Hyperlipoproteinemia
  • Post prandial lipemia
  • Triglycerides

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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