Abstract
A novel and convenient microwave-assisted synthesis of 1,2,4-oxadiazoles is described. Conventional heating and microwave irradiation of the reactions are compared. Moreover, the importance of some coupling reagents was evaluated. One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.
Original language | English |
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Pages (from-to) | 4491-4493 |
Number of pages | 3 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 14 |
Issue number | 17 |
DOIs | |
Publication status | Published - Sep 6 2004 |
Keywords
- 1,2,4-Oxadiazoles
- Microwave irradiation
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Organic Chemistry
- Drug Discovery
- Pharmaceutical Science