A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

Vincenzo Santagada; Francesco Frecentese; Elisa Perissutti; Donatella Cirillo; Sara Terracciano; Giuseppe Caliendo

doi:10.1016/j.bmcl.2004.06.048

A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

Vincenzo Santagada, Francesco Frecentese, Elisa Perissutti, Donatella Cirillo, Sara Terracciano, Giuseppe Caliendo

Istituto Nazionale Tumori Fondazione G. Pascale

Research output: Contribution to journal › Article › peer-review

Abstract

A novel and convenient microwave-assisted synthesis of 1,2,4-oxadiazoles is described. Conventional heating and microwave irradiation of the reactions are compared. Moreover, the importance of some coupling reagents was evaluated. One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.

Original language	English
Pages (from-to)	4491-4493
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	14
Issue number	17
DOIs	https://doi.org/10.1016/j.bmcl.2004.06.048
Publication status	Published - Sep 6 2004

Keywords

1,2,4-Oxadiazoles
Microwave irradiation

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Organic Chemistry
Drug Discovery
Pharmaceutical Science

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10.1016/j.bmcl.2004.06.048

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abstract = "A novel and convenient microwave-assisted synthesis of 1,2,4-oxadiazoles is described. Conventional heating and microwave irradiation of the reactions are compared. Moreover, the importance of some coupling reagents was evaluated. One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.",

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AU - Santagada, Vincenzo

AU - Frecentese, Francesco

AU - Perissutti, Elisa

AU - Cirillo, Donatella

AU - Terracciano, Sara

AU - Caliendo, Giuseppe

PY - 2004/9/6

Y1 - 2004/9/6

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AB - A novel and convenient microwave-assisted synthesis of 1,2,4-oxadiazoles is described. Conventional heating and microwave irradiation of the reactions are compared. Moreover, the importance of some coupling reagents was evaluated. One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.

KW - 1,2,4-Oxadiazoles

KW - Microwave irradiation

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ER -

A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

Abstract

Keywords

ASJC Scopus subject areas

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