A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

Vincenzo Santagada; Francesco Frecentese; Elisa Perissutti; Donatella Cirillo; Sara Terracciano; Giuseppe Caliendo

doi:10.1016/j.bmcl.2004.06.048

A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

Vincenzo Santagada, Francesco Frecentese, Elisa Perissutti, Donatella Cirillo, Sara Terracciano, Giuseppe Caliendo

Istituto Nazionale Tumori Fondazione G. Pascale

Research output: Contribution to journal › Article › peer-review

Abstract

A novel and convenient microwave-assisted synthesis of 1,2,4-oxadiazoles is described. Conventional heating and microwave irradiation of the reactions are compared. Moreover, the importance of some coupling reagents was evaluated. One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.

Original language	English
Pages (from-to)	4491-4493
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	14
Issue number	17
DOIs	https://doi.org/10.1016/j.bmcl.2004.06.048
Publication status	Published - Sep 6 2004

Keywords

1,2,4-Oxadiazoles
Microwave irradiation

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Organic Chemistry
Drug Discovery
Pharmaceutical Science

Access to Document

10.1016/j.bmcl.2004.06.048

Fingerprint Dive into the research topics of 'A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation'. Together they form a unique fingerprint.

Cite this

@article{38d566fe796c4cb982a122c12eb38f20,

title = "A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation",

abstract = "A novel and convenient microwave-assisted synthesis of 1,2,4-oxadiazoles is described. Conventional heating and microwave irradiation of the reactions are compared. Moreover, the importance of some coupling reagents was evaluated. One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.",

keywords = "1,2,4-Oxadiazoles, Microwave irradiation",

author = "Vincenzo Santagada and Francesco Frecentese and Elisa Perissutti and Donatella Cirillo and Sara Terracciano and Giuseppe Caliendo",

year = "2004",

month = sep,

day = "6",

doi = "10.1016/j.bmcl.2004.06.048",

language = "English",

volume = "14",

pages = "4491--4493",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Limited",

number = "17",

}

TY - JOUR

T1 - A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

AU - Santagada, Vincenzo

AU - Frecentese, Francesco

AU - Perissutti, Elisa

AU - Cirillo, Donatella

AU - Terracciano, Sara

AU - Caliendo, Giuseppe

PY - 2004/9/6

Y1 - 2004/9/6

N2 - A novel and convenient microwave-assisted synthesis of 1,2,4-oxadiazoles is described. Conventional heating and microwave irradiation of the reactions are compared. Moreover, the importance of some coupling reagents was evaluated. One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.

AB - A novel and convenient microwave-assisted synthesis of 1,2,4-oxadiazoles is described. Conventional heating and microwave irradiation of the reactions are compared. Moreover, the importance of some coupling reagents was evaluated. One pot microwave-assisted synthesis of substituted 1,2,4-oxadiazoles in solvent and under solvent free condition was performed exploring the importance of some coupling reagents. Good yields and short reaction times were the main aspects of the methods.

KW - 1,2,4-Oxadiazoles

KW - Microwave irradiation

UR - http://www.scopus.com/inward/record.url?scp=3843097357&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3843097357&partnerID=8YFLogxK

U2 - 10.1016/j.bmcl.2004.06.048

DO - 10.1016/j.bmcl.2004.06.048

M3 - Article

C2 - 15357978

AN - SCOPUS:3843097357

VL - 14

SP - 4491

EP - 4493

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

SN - 0960-894X

IS - 17

ER -

A suitable 1,2,4-oxadiazoles synthesis by microwave irradiation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this