A supervised CAD to support telemedicine in hematology

Vitoantonio Bevilacqua, Domenico Buongiorno, Pierluigi Carlucci, Ferdinando Giglio, Giacomo Tattoli, Attilio Guarini, Nicola Sgherza, Giacoma De Tullio, Carla Minoia, Anna Scattone, Giovanni Simone, Francesco Girardi, Alfredo Zito, Loreto Gesualdo

Research output: Chapter in Book/Report/Conference proceedingConference contribution


This paper presents the design and the implementation of a Computer Aided Diagnosis (CAD) system for the clinical analysis of Peripheral Blood Smears (PBS also called Blood Film). The proposed system is able to count and classify the five types of leucocytes located in the tail of a PBS for computing the leukocyte formula. Image processing and segmentation techniques were used to extract 33 leucocyte's features (morphological, chromatic and texture-based). Only 7 features, selected by using the Information Gain Ranking algorithm of Weka platform, were used to evaluate the classification performance of two different classifiers: Back Propagation Neural Network (BPNN) and Decision Tree (DT). From the comparison between the two proposed approaches we can argue that the BPNN performed better than the DT on the validation set. Finally, the Neural Network classifier was evaluated with a test set composed of 1274 leucocytes obtaining good results in terms of Precision (87.9%) and Sensitivity (97.4%).

Original languageEnglish
Title of host publicationProceedings of the International Joint Conference on Neural Networks
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781479919604, 9781479919604, 9781479919604, 9781479919604
Publication statusPublished - Sep 28 2015
EventInternational Joint Conference on Neural Networks, IJCNN 2015 - Killarney, Ireland
Duration: Jul 12 2015Jul 17 2015


OtherInternational Joint Conference on Neural Networks, IJCNN 2015


  • Blood
  • Complexity theory
  • Image coding
  • Image resolution
  • Plasmas
  • Training

ASJC Scopus subject areas

  • Software
  • Artificial Intelligence


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