Abstract
D-dimer assessment represents a cornerstone in the diagnostic approach and therapeutic management of several thrombotic disorders, namely venous thromboembolism and disseminated intravascular coagulation. Nevertheless, this test is still plagued by an insufficient degree of analytical and post-analytical standardization. In particular, despite the existence of national guidelines, result reporting is quite heterogeneous. A specific on-line, 5-item questionnaire was disseminated to the SIBioC members to obtain a picture of the current national situation. As regards to the units, a modest prevalence (53%) of D-dimer unit (DDU) over fibrinogen equivalent unit (FEU) (47%) was found. The most widespread measurement unit was "ng/mL" (60%), followed by "μg/L" (18%), "mg/L" (15%) and "μg/mL" (6%). The vast majority of laboratories (90%) did not use an age-adjusted cut-off. The data distribution did not differ among different types of healthcare settings (i.e., general hospital, university hospital or private facilities). The use of at least 16 different unit approaches for D-dimer emerged from the survey is quite alarming and calls for a standardization, using a single result reporting as .
| Original language | Italian |
|---|---|
| Pages (from-to) | 591-594 |
| Number of pages | 4 |
| Journal | Biochimica Clinica |
| Volume | 39 |
| Issue number | 6 |
| Publication status | Published - 2015 |
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ASJC Scopus subject areas
- Clinical Biochemistry
- Biochemistry, medical
- Medical Laboratory Technology
Cite this
Indagine sulla modalità di refertazione dell'esame D-dimero nei laboratori nazionali e indicazioni per una sua armonizzazione. / Lippi, Giuseppe; Morelli, Benedetto; Tripodi, Armando.
In: Biochimica Clinica, Vol. 39, No. 6, 2015, p. 591-594.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Indagine sulla modalità di refertazione dell'esame D-dimero nei laboratori nazionali e indicazioni per una sua armonizzazione
AU - Lippi, Giuseppe
AU - Morelli, Benedetto
AU - Tripodi, Armando
PY - 2015
Y1 - 2015
N2 - D-dimer assessment represents a cornerstone in the diagnostic approach and therapeutic management of several thrombotic disorders, namely venous thromboembolism and disseminated intravascular coagulation. Nevertheless, this test is still plagued by an insufficient degree of analytical and post-analytical standardization. In particular, despite the existence of national guidelines, result reporting is quite heterogeneous. A specific on-line, 5-item questionnaire was disseminated to the SIBioC members to obtain a picture of the current national situation. As regards to the units, a modest prevalence (53%) of D-dimer unit (DDU) over fibrinogen equivalent unit (FEU) (47%) was found. The most widespread measurement unit was "ng/mL" (60%), followed by "μg/L" (18%), "mg/L" (15%) and "μg/mL" (6%). The vast majority of laboratories (90%) did not use an age-adjusted cut-off. The data distribution did not differ among different types of healthcare settings (i.e., general hospital, university hospital or private facilities). The use of at least 16 different unit approaches for D-dimer emerged from the survey is quite alarming and calls for a standardization, using a single result reporting as .
AB - D-dimer assessment represents a cornerstone in the diagnostic approach and therapeutic management of several thrombotic disorders, namely venous thromboembolism and disseminated intravascular coagulation. Nevertheless, this test is still plagued by an insufficient degree of analytical and post-analytical standardization. In particular, despite the existence of national guidelines, result reporting is quite heterogeneous. A specific on-line, 5-item questionnaire was disseminated to the SIBioC members to obtain a picture of the current national situation. As regards to the units, a modest prevalence (53%) of D-dimer unit (DDU) over fibrinogen equivalent unit (FEU) (47%) was found. The most widespread measurement unit was "ng/mL" (60%), followed by "μg/L" (18%), "mg/L" (15%) and "μg/mL" (6%). The vast majority of laboratories (90%) did not use an age-adjusted cut-off. The data distribution did not differ among different types of healthcare settings (i.e., general hospital, university hospital or private facilities). The use of at least 16 different unit approaches for D-dimer emerged from the survey is quite alarming and calls for a standardization, using a single result reporting as .
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M3 - Articolo
AN - SCOPUS:84959361323
VL - 39
SP - 591
EP - 594
JO - Biochimica Clinica
JF - Biochimica Clinica
SN - 0393-0564
IS - 6
ER -