A systematic literature review of factors affecting outcome in older medical patients admitted to hospital

Susan E. Campbell, D. Gwyn Seymour, Willie R. Primrose, Cari Almazan, Sergio Arino, Edmund Dunstan, Mireia Espallargues, Ahmed Abdel Hafiz, Giovanni Lamura, Peter Lawson, Janusz Lewko, Joanna Lynch, Elizabeth Mestheneous, Ian Philp, Barbara Politynska, Costis Prouskas, Sabrina Quattrini, Ismo Raiha, Tapio Rajala, Judy Triantafillou

Research output: Contribution to journalArticle

241 Citations (Scopus)

Abstract

Introduction: the ACMEplus project aims to devise a standardised system for measuring case-mix and outcome in older patients admitted to hospitals in different parts of Europe for primarily 'medical' (i.e. not surgical or psychiatric) reasons. As a first step in this project, a systematic review was carried out to identify factors which had a significant influence on outcome in such patients. Methods: the systematic search used Medline 1966-2000, Cinahl 1982-2000, Web of Science 1981-2000, reference lists of relevant papers and a hand search of Age and Ageing 1974-2000. A six-category grading system was devised to classify the 313 identified papers with regard to their relevance to the ACMEplus project, study design and power. The analysis of the 14 'category 1' papers is presented. Results: the main areas of assessment of case-mix were function, cognition, depression, illness severity, nutrition, social elements, aspects of diagnosis and demographic details. Statistically significant predictors, for the four outcome measures, listed below were: i For length of stay: functional status score, illness severity, cognitive score, poor nutrition, comorbidity score, diagnosis or presenting illness, polypharmacy, age and gender. ii For mortality: functional status score, illness severity, cognitive score, comorbidity score, diagnosis or presenting illness, polypharmacy, age and gender. iii For discharge destination: functional status score, cognitive score, diagnosis or presenting illness and age. iv For readmission rate: functional status score, illness severity, co-morbidity, polypharmacy, diagnosis or presenting illness and age. Conclusions: factors affecting outcome in older medical patients are complex. When looking at outcomes of hospital admission in older people it is important not just to look at routinely available statistics such as age, gender and diagnosis but also to take into account multifaceted aspects such as functional status and cognitive function.

Original languageEnglish
Pages (from-to)110-115
Number of pages6
JournalAge and Ageing
Volume33
Issue number2
DOIs
Publication statusPublished - Mar 2004

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Polypharmacy
Diagnosis-Related Groups
Cognition
Comorbidity
Psychiatry
Length of Stay
Demography
Outcome Assessment (Health Care)
Depression
Morbidity
Mortality

Keywords

  • Age (80 years and over)
  • Elderly
  • Hospital admission
  • Length of stay
  • Outcome assessment (health care0
  • Prognosis
  • Prospective studies
  • Systematic review

ASJC Scopus subject areas

  • Ageing

Cite this

Campbell, S. E., Seymour, D. G., Primrose, W. R., Almazan, C., Arino, S., Dunstan, E., ... Triantafillou, J. (2004). A systematic literature review of factors affecting outcome in older medical patients admitted to hospital. Age and Ageing, 33(2), 110-115. https://doi.org/10.1093/ageing/afh036

A systematic literature review of factors affecting outcome in older medical patients admitted to hospital. / Campbell, Susan E.; Seymour, D. Gwyn; Primrose, Willie R.; Almazan, Cari; Arino, Sergio; Dunstan, Edmund; Espallargues, Mireia; Hafiz, Ahmed Abdel; Lamura, Giovanni; Lawson, Peter; Lewko, Janusz; Lynch, Joanna; Mestheneous, Elizabeth; Philp, Ian; Politynska, Barbara; Prouskas, Costis; Quattrini, Sabrina; Raiha, Ismo; Rajala, Tapio; Triantafillou, Judy.

In: Age and Ageing, Vol. 33, No. 2, 03.2004, p. 110-115.

Research output: Contribution to journalArticle

Campbell, SE, Seymour, DG, Primrose, WR, Almazan, C, Arino, S, Dunstan, E, Espallargues, M, Hafiz, AA, Lamura, G, Lawson, P, Lewko, J, Lynch, J, Mestheneous, E, Philp, I, Politynska, B, Prouskas, C, Quattrini, S, Raiha, I, Rajala, T & Triantafillou, J 2004, 'A systematic literature review of factors affecting outcome in older medical patients admitted to hospital', Age and Ageing, vol. 33, no. 2, pp. 110-115. https://doi.org/10.1093/ageing/afh036
Campbell, Susan E. ; Seymour, D. Gwyn ; Primrose, Willie R. ; Almazan, Cari ; Arino, Sergio ; Dunstan, Edmund ; Espallargues, Mireia ; Hafiz, Ahmed Abdel ; Lamura, Giovanni ; Lawson, Peter ; Lewko, Janusz ; Lynch, Joanna ; Mestheneous, Elizabeth ; Philp, Ian ; Politynska, Barbara ; Prouskas, Costis ; Quattrini, Sabrina ; Raiha, Ismo ; Rajala, Tapio ; Triantafillou, Judy. / A systematic literature review of factors affecting outcome in older medical patients admitted to hospital. In: Age and Ageing. 2004 ; Vol. 33, No. 2. pp. 110-115.
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