A Systematic Review with Consensus Expert Opinion of Best Reconstructive Techniques after Osseous Enbloc Spinal Column Tumor Resection

Andrew A. Glennie, Raja R. Rampersaud, Stefano Boriani, Jeremy Reynolds, Richard Williams, Ziya L. Gokaslan, Meic Schmidt, Peter Varga, Charles G. Fisher

Research output: Contribution to journalArticlepeer-review

Abstract

STUDY DESIGN.: Systematic literature review and consensus expert opinion OBJECTIVE.: To provide recommendations on reconstructive constructs for large tumor resections of the spinal column. Four questions were studied: SUMMARY OF BACKGROUND DATA.: Primary spinal tumors requiring en bloc resection are rare. Most studies focus on disease-free survival and local recurrence rates. Few studies focus on reconstructive options and outcomes with respect to fusion rates and need for revision. METHODS.: A literature search was performed from January 1990-December 2013. Data were combined and construct survivorship summarized. A survey was administered to international spine tumor surgeons, evaluating reconstructive preferences. RESULTS.: The search yielded 381 articles, 12 included in the final analysis. Revision rates for anterior reconstruction were similar for autogenous strut grafts (10%), cages (7.7%), and allograft strut grafts (8.3%). There were 2 reports of revision from short to long segment constructs and 3 reports of broken pedicle screws, one requiring revision. Expert survey results revealed that most surgeons preferred cages packed with morcelized allograft and autograft (75%) for anterior reconstruction of single-level vertebrectomies, and strut bone grafting at the cervicothoracic junction (65%) and when more than one vertebrae was resected in the mid-thoracic spine (75%). Surgeons may alter their fusion technique if postoperative radiation is planned. CONCLUSION.: Posterior reconstruction with at least two vertebral levels above and below is recommended. Cages should be used for single-level defects and structural bone graft alone, or in combination with a cage, should be used when spanning a defect greater than two vertebral bodies. Planned postoperative radiation may affect fusion strategy.

Original languageEnglish
JournalSpine
DOIs
Publication statusAccepted/In press - Aug 3 2016

ASJC Scopus subject areas

  • Clinical Neurology
  • Orthopedics and Sports Medicine

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