Abstract
Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.
Original language | English |
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Pages (from-to) | 644-646 |
Number of pages | 3 |
Journal | Neurology |
Volume | 52 |
Issue number | 3 |
Publication status | Published - Feb 1999 |
ASJC Scopus subject areas
- Neuroscience(all)