A tentative interpretation of electromyographic regional differences in bulbar- and limb-onset ALS

A. Cappellari; A. Brioschi; S. Barbieri; M. Braga; G. Scarlato; Vincenzo Silani

A tentative interpretation of electromyographic regional differences in bulbar- and limb-onset ALS

A. Cappellari, A. Brioschi, S. Barbieri, M. Braga, G. Scarlato, Vincenzo Silani

Research output: Contribution to journal › Article › peer-review

Abstract

Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.

Original language	English
Pages (from-to)	644-646
Number of pages	3
Journal	Neurology
Volume	52
Issue number	3
Publication status	Published - Feb 1999

ASJC Scopus subject areas

Neuroscience(all)

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abstract = "Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.",

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AU - Cappellari, A.

AU - Brioschi, A.

AU - Barbieri, S.

AU - Braga, M.

AU - Scarlato, G.

AU - Silani, Vincenzo

PY - 1999/2

Y1 - 1999/2

N2 - Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.

AB - Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.

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A tentative interpretation of electromyographic regional differences in bulbar- and limb-onset ALS

Abstract

ASJC Scopus subject areas

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