Abstract
Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.
| Original language | English |
|---|---|
| Pages (from-to) | 644-646 |
| Number of pages | 3 |
| Journal | Neurology |
| Volume | 52 |
| Issue number | 3 |
| Publication status | Published - Feb 1999 |
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ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Cappellari, A., Brioschi, A., Barbieri, S., Braga, M., Scarlato, G., & Silani, V. (1999). A tentative interpretation of electromyographic regional differences in bulbar- and limb-onset ALS. Neurology, 52(3), 644-646.