Abstract
A to O bone marrow transplantation was performed in a 25 yr old male affected with severe aplastic anemia, the donor being an HLA compatible brother. Three plasma exchanges had to be performed with an Aminco separator to remove the original and recurring anti A isohemagglutinins. The dynamics of O to A blood group conversion were followed by means of differential agglutination. An early wave of marked dyserythropoiesis was observed in the engrafted marrow. Mild to moderate GvHD was treated successfully with MTX, bolus high dosage 6 methylprednisolone and, at relapse, with intravenous ALG.
| Original language | English |
|---|---|
| Pages (from-to) | 511-518 |
| Number of pages | 8 |
| Journal | British Journal of Haematology |
| Volume | 36 |
| Issue number | 4 |
| Publication status | Published - 1977 |
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ASJC Scopus subject areas
- Hematology
Cite this
A to O bone marrow transplantation in severe aplastic anaemia : dynamics of blood group conversion and demonstration of early dyserythropoiesis in the engrafted marrow. / Marmont, A. M.; Damasio, E. E.; Bacigalupo, A.; Giordano, D.; Rossi, E.; Reali, G.; Gay, A.; Dagna-Bricarelli, F.; Brema, F.; Carella, A. M.; Santini, G.
In: British Journal of Haematology, Vol. 36, No. 4, 1977, p. 511-518.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A to O bone marrow transplantation in severe aplastic anaemia
T2 - dynamics of blood group conversion and demonstration of early dyserythropoiesis in the engrafted marrow
AU - Marmont, A. M.
AU - Damasio, E. E.
AU - Bacigalupo, A.
AU - Giordano, D.
AU - Rossi, E.
AU - Reali, G.
AU - Gay, A.
AU - Dagna-Bricarelli, F.
AU - Brema, F.
AU - Carella, A. M.
AU - Santini, G.
PY - 1977
Y1 - 1977
N2 - A to O bone marrow transplantation was performed in a 25 yr old male affected with severe aplastic anemia, the donor being an HLA compatible brother. Three plasma exchanges had to be performed with an Aminco separator to remove the original and recurring anti A isohemagglutinins. The dynamics of O to A blood group conversion were followed by means of differential agglutination. An early wave of marked dyserythropoiesis was observed in the engrafted marrow. Mild to moderate GvHD was treated successfully with MTX, bolus high dosage 6 methylprednisolone and, at relapse, with intravenous ALG.
AB - A to O bone marrow transplantation was performed in a 25 yr old male affected with severe aplastic anemia, the donor being an HLA compatible brother. Three plasma exchanges had to be performed with an Aminco separator to remove the original and recurring anti A isohemagglutinins. The dynamics of O to A blood group conversion were followed by means of differential agglutination. An early wave of marked dyserythropoiesis was observed in the engrafted marrow. Mild to moderate GvHD was treated successfully with MTX, bolus high dosage 6 methylprednisolone and, at relapse, with intravenous ALG.
UR - http://www.scopus.com/inward/record.url?scp=0017644080&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017644080&partnerID=8YFLogxK
M3 - Article
VL - 36
SP - 511
EP - 518
JO - British Journal of Haematology
JF - British Journal of Haematology
SN - 0007-1048
IS - 4
ER -