A tumour associated membrane antigen transiently expressed by normal cells during mitosis

M. Bertini, G. Forni, P. M. Comoglio

Research output: Contribution to journalArticle

Abstract

Rabbit antisera raised against antigens solubilized from the membranes of a transplantable Balb/c adenocarcinoma precipitated an antigen that was not expressed by the normal resting mammary gland or any other normal mouse tissue. The same antisera were used to show the presence of this antigen in other mammary adenocarcinomas, although not in tumor of different histological types. The antigen was, however, transiently expressed by mammary gland cells during the hyperplasia that both precedes and accompanies lactation. A connection is sought between the existence of this antigen and the membrane structural changes that take place during mitosis.

Original languageEnglish
Pages (from-to)101-108
Number of pages8
JournalClinical and Experimental Immunology
Volume18
Issue number1
Publication statusPublished - 1974

ASJC Scopus subject areas

  • Immunology

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