A wearable proprioceptive stabilizer for rehabilitation of limb and gait ataxia in hereditary cerebellar ataxias: a pilot open-labeled study

Luca Leonardi, Maria Gabriella Aceto, Christian Marcotulli, Giuseppe Arcuria, Mariano Serrao, Francesco Pierelli, Paolo Paone, Alessandro Filla, Alessandro Roca, Carlo Casali

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The aim of this pilot study is to test the feasibility and effectiveness of a wearable proprioceptive stabilizer that emits focal mechanical vibrations in patients affected by hereditary cerebellar ataxias. Eleven adult patients with a confirmed genetic diagnosis of autosomal dominant spinocerebellar ataxia or Friedreich's ataxia were asked to wear an active device for 3 weeks. Assessments were performed at baseline, after the device use (T1), and 3 weeks after (T2). SARA, 9-HPT, PATA, 6MWT, and spatial and temporal gait parameters, measured with a BTS-G-Walk inertial sensor, were used as study endpoints. As expected, no adverse effects were reported. Statistically significant improvements in SARA, 9HPT dominant hand, PATA test, 6MWT, cadence, length cycle, support right/cycle, support left/cycle, flight right/cycle, flight left/cycle, double support right/cycle, double support left/cycle, single support right/cycle, and single support left/cycle were observed between T0 and T1. All parameters improved at T1 did not show statistically significant differences a T2, with the exception of length of cycle. This small open-labeled study shows preliminary evidence that focal mechanical vibration exerted by a wearable proprioceptive stabilizer might improve limb and gait ataxia in patients affected by hereditary cerebellar ataxias.

Original languageEnglish
Pages (from-to)459-463
Number of pages5
JournalNeurological Sciences
Volume38
Issue number3
DOIs
Publication statusPublished - Mar 2017

Fingerprint

Gait Ataxia
Spinocerebellar Degenerations
Cerebellar Ataxia
Ataxia
Rehabilitation
Vibration
Friedreich Ataxia
Spinocerebellar Ataxias
Equipment and Supplies
Gait
Hand

Keywords

  • Feedback, Sensory
  • Female
  • Friedreich Ataxia
  • Gait Ataxia
  • Humans
  • Male
  • Physical Therapy Modalities
  • Pilot Projects
  • Spinocerebellar Ataxias
  • Vibration
  • Clinical Trial
  • Journal Article

Cite this

A wearable proprioceptive stabilizer for rehabilitation of limb and gait ataxia in hereditary cerebellar ataxias : a pilot open-labeled study. / Leonardi, Luca; Aceto, Maria Gabriella; Marcotulli, Christian; Arcuria, Giuseppe; Serrao, Mariano; Pierelli, Francesco; Paone, Paolo; Filla, Alessandro; Roca, Alessandro; Casali, Carlo.

In: Neurological Sciences, Vol. 38, No. 3, 03.2017, p. 459-463.

Research output: Contribution to journalArticle

Leonardi, Luca ; Aceto, Maria Gabriella ; Marcotulli, Christian ; Arcuria, Giuseppe ; Serrao, Mariano ; Pierelli, Francesco ; Paone, Paolo ; Filla, Alessandro ; Roca, Alessandro ; Casali, Carlo. / A wearable proprioceptive stabilizer for rehabilitation of limb and gait ataxia in hereditary cerebellar ataxias : a pilot open-labeled study. In: Neurological Sciences. 2017 ; Vol. 38, No. 3. pp. 459-463.
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