Abdominopelvic radiotherapy following surgery and chemotherapy in advanced ovarian cancer

Silvana Chiara, M. Orsatti, Paola Franzone, D. Scarpati, Milena Bruzzone, L. Repetto, V. Vitale, P. F. Conte, R. Rosso

Research output: Contribution to journalArticlepeer-review

Abstract

Thirty advanced ovarian cancer patients have been treated with sequential multimodality treatment including primary surgery, cisplatin or carboplatin-based polichemotherapy, second-look laparotomy followed by abdominopelvic irradiation (moving strip or open-field technique). Toxicity related to the combined treatment was acceptable: only three patients failed to complete and two patients delayed the prescribed course of radiotherapy because of acute myelosuppression or gastroenteric disturbances. One patient without evidence of disease required laparotomy for bowel obstruction one month after completion of radiotherapy. No other chronic toxicity of clinical significance has been observed. Actuarial three-year survival significantly correlated with residual disease at the start of radiotherapy: no residuum, 100%, microscopic disease, 52%;

Original languageEnglish
Pages (from-to)340-344
Number of pages5
JournalClinical Oncology
Volume3
Issue number6
DOIs
Publication statusPublished - 1991

Keywords

  • Abdominopelvic radiotherapy
  • Ovarian cancer

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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